DBI

Gene Symbol	DBI
Entrez Gene	1622
Alt Symbol	ACBD1, ACBP, CCK-RP, EP
Species	Human
Gene Type	protein-coding
Description	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
Other Description	GABA receptor modulator|acyl coenzyme A binding protein|acyl-CoA-binding protein|acyl-Coenzyme A binding domain containing 1|cholecystokinin-releasing peptide, trypsin-sensitive|diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein)|diazepam-binding inhibitor|endozepine
Swissprots	B8ZWD2 P07108 Q6IB48 B8ZWD6 B8ZWD7 Q9UCI8 P08869 Q53SQ7 Q4VWZ6
Accessions	AAY14873 EAW95214 EAW95215 EAW95216 P07108 AA096224 AM000001 CAJ00736 BC006466 BC062996 AAH62996 BM768076 BP294452 BP318721 BU599304 CR456956 CAG33237 DA226476 FM213122 CAR82404 FM213123 CAR82405 FM213124 CAR82406 FM213125 CAR82407 FM213126 CAR82408 FM213127 CAR82409 FM213128 CAR82410 FM213129 CAR82411 FM213130 CAR82412 FM213131 CAR82414 HQ448654 ADQ33132 M14200 AAA52171 M15887 AAA35788 NM_001079862 NP_001073331 NM_001079863 NP_001073332 NM_001178017 NP_001171488 NM_001178041 NP_001171512 NM_001178042 NP_001171513 NM_001178043 NP_001171514 NM_001282633 NP_001269562 NM_001282634 NP_001269563 NM_001282635 NP_001269564 NM_001282636 NP_001269565 NM_020548 NP_065438 NR_104221
Function	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
Subcellular Location	Endoplasmic reticulum. Golgi apparatus. Note=Golgi localization is dependent on ligand binding.
Tissue Specificity	Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart. {ECO:0000269|PubMed:16055366, ECO:0000269|PubMed:21698759}.
Top Pathways	PPAR signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Diazepam Binding Inhibitor full length protein - ab95485 from Abcam Category Protein Source E. coli Species Human

Human Diazepam Binding Inhibitor full length protein - ab84342 from Abcam Category Protein Source E. coli Species Human

DBI / ACBD1 Antibody Blocking Peptide - LS-E11680 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACBP Partial Recombinant Protein - H00001622-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 2 µg Species Human

ACBP Recombinant Protein - H00001622-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ACBP Protein - NBP1-44453 from Novus Biologicals Category Protein Species Human

Recombinant Human ACBP Protein - NBP1-50833 from Novus Biologicals Category Protein Prices $269.00, $649.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Diazepam-Binding-Inhibitor-Fragment-human - SP2108b from Abgent, a WuXi AppTec company Category Peptide Prices $375.00 Sizes 5 mg Species Human

Diazepam-Binding-Inhibitor-Fragment-human - SP2108a from Abgent, a WuXi AppTec company Category Peptide Prices $132.00 Sizes 1 mg Species Human

DBI Protein (OPPA02287) - OPPA02287 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human DBI protein (His Tag) - orb138679 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source E. coli Species Human

Human DBI protein - orb81065 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 25 μg Species Human

Human DBI protein - orb244155 from Biorbyt Category Protein Prices $315.00, $502.00, $782.00, $1,139.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

ACBP protein (His tag) - 80R-1331 from Fitzgerald Category Protein Prices $220.00 Sizes 100 µg Source E.coli

DBI Blocking Peptide - 33R-6477 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Diazepam Binding Inhibitor protein - 30R-3011 from Fitzgerald Category Protein Prices $175.00 Sizes 500 µg Source E.coli

EPO beta protein - 30R-2701 from Fitzgerald Category Protein Prices $410.00 Sizes 500 iu Source CHO cells Species Human

EPO protein - 30R-AE009 from Fitzgerald Category Protein Prices $295.00, $925.00 Sizes 50 µg, 500 µg Source CHO cells

IL1 alpha protein - 30R-AI017 from Fitzgerald Category Protein Prices $225.00 Sizes 10 µg Source E.coli

Ricin Acyl CoA binding protein (His tag) - 80-1054 from Fitzgerald Category Protein Prices $325.00 Sizes 200 µg Source E.coli Species Ricinus communis

Human DBI Protein - abx066328 from Abbexa Category Protein Source E.coli Species Human

DBI / ACBP (1-87, His-tag) - AR09477PU-L from Acris Antibodies Category Protein Prices $695.00 Sizes 500 µg Source E. coli Species Human

DBI / ACBP (1-87, His-tag) - AR09477PU-N from Acris Antibodies Category Protein Prices $305.00 Sizes 100 µg Source E. coli Species Human

DBI / ACBP - H00001622-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DBI / ACBP - H00001622-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

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