Gene Symbol | PDCD10 |
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Entrez Gene | 11235 |
Alt Symbol | CCM3, TFAR15 |
Species | Human |
Gene Type | protein-coding |
Description | programmed cell death 10 |
Other Description | TF-1 cell apoptosis-related protein 15|apoptosis-related protein 15|cerebral cavernous malformations 3 protein|programmed cell death protein 10 |
Swissprots | O14811 D3DNN5 A8K515 Q9BUL8 |
Accessions | EAW78574 EAW78575 EAW78576 EAW78577 EAW78578 EAW78579 EAW78580 EAW78581 Q9BUL8 AF022385 AAB72225 AK291130 BAF83819 BC002506 AAH02506 BC016353 AAH16353 CR457107 CAG33388 DQ892583 ABM83509 DQ895799 ABM86725 XM_005247086 XP_005247143 XM_005247087 XP_005247144 XM_005247088 XP_005247145 XM_006713485 XP_006713548 XM_011512368 XP_011510670 XM_011512369 XP_011510671 XM_011512370 XP_011510672 NM_007217 NP_009148 NM_145859 NP_665858 NM_145860 NP_665859 |
Function | Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Partially co- localizes with endogenous PXN at the leading edges of migrating cells. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:15543491}. |
CCM3 (F-12) - sc-365587 from Santa Cruz Biotechnology
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CCM3 (C-8) - sc-365586 from Santa Cruz Biotechnology
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CCM3 (H-189) - sc-135268 from Santa Cruz Biotechnology
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CCM3 (L-20) - sc-67908 from Santa Cruz Biotechnology
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CCM3 (E-15) - sc-67907 from Santa Cruz Biotechnology
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Anti-PDCD10 antibody - ab180706 from Abcam
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Anti-PDCD10 antibody - ab111507 from Abcam
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Anti-PDCD10 Antibody (aa96-124, Biotin) - LS-C265841 from LifeSpan Bioscience
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Anti-PDCD10 Antibody (aa96-124, FITC) - LS-C265842 from LifeSpan Bioscience
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Anti-PDCD10 Antibody (aa96-124, Azide-free, HRP) - LS-C265843 from LifeSpan Bioscience
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Anti-PDCD10 Antibody (aa96-124, PE) - LS-C265844 from LifeSpan Bioscience
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Anti-PDCD10 Antibody (aa96-124, AP) - LS-C284506 from LifeSpan Bioscience
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Anti-PDCD10 Antibody (aa95-124) - LS-C323874 from LifeSpan Bioscience
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Anti-PDCD10 Antibody (aa96-124, APC) - LS-C284507 from LifeSpan Bioscience
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Anti-PDCD10 Antibody - LS-C341490 from LifeSpan Bioscience
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Anti-PDCD10 Antibody (aa96-124) - LS-C158556 from LifeSpan Bioscience
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Anti-PDCD10 Antibody - LS-C332244 from LifeSpan Bioscience
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PDCD10 Antibody - NBP1-47195 from Novus Biologicals
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PDCD10 Antibody - NBP1-86574 from Novus Biologicals
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PDCD10 Antibody (1B11) - H00011235-M05-100ug from Novus Biologicals
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PDCD10 Polyclonal Antibody - bs-6847R from Bioss
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Monoclonal Anti-PDCD10 antibody produced in mouse - SAB1412804 from Sigma-Aldrich
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Anti-PDCD10 antibody produced in rabbit - HPA027095 from Sigma-Aldrich
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ANTI-PDCD10 (CENTER) antibody produced in rabbit - SAB1305161 from Sigma-Aldrich
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PDCD10-Antibody-Center - AP17989c from Abgent, a WuXi AppTec company
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