ST3GAL2

Gene Symbol ST3GAL2
Entrez Gene 6483
Alt Symbol Gal-NAc6S, SIAT4B, ST3GALII, ST3GalA.2
Species Human
Gene Type protein-coding
Description ST3 beta-galactoside alpha-2,3-sialyltransferase 2
Other Description CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2|Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase|SIAT4-B|ST3Gal II|alpha 2,3-ST 2|beta-galactoside alpha-2,3-sialyltransferase 2|beta-galactoside alpha-2,3-sialytransferase|sialyltransferase 4B (beta-galactosidase alpha-2,3-sialytransferase)
Swissprots O00654 Q16842
Accessions CAS91689 EAW51818 EAW51819 EAW51820 EAW51821 Q16842 AF086257 AI933719 AK127322 BAG54481 AK313020 BAG35855 BC036777 AAH36777 BC064480 BI832366 JF432706 ADZ15923 U63090 AAB40389 X96667 CAA65447 NM_006927 NP_008858
Function It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found in terminal carbohydrate groups of certain glycoproteins, oligosaccharides and glycolipids. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values.
Subcellular Location Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Secreted {ECO:0000250}. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid (By similarity). {ECO:0000250}.
Tissue Specificity Highly expressed in skeletal muscle and heart and to a much lesser extent in brain, placenta, liver and pancreas. Scarcely detectable in lung and kidney. {ECO:0000269|PubMed:8920913, ECO:0000269|PubMed:9266697}.
Top Pathways Mucin type O-Glycan biosynthesis, Glycosaminoglycan biosynthesis - keratan sulfate, Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - ganglio series

Human ST3GAL2 full length protein - ab159509 from Abcam

Category Protein
Source Wheat germ
Species Human
ab159509 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human ST3GAL2 protein fragment - ab159510 from Abcam

Category Protein
Source Wheat germ
Species Human
ab159510 on a 12.5% SDS-PAGE stained with Coomassie Blue.

ST3 beta-Gal alpha-2,3-Sialyltransferase 2/ST3GAL2 Partial Recombinant Protein - H00006483-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human ST3 beta-Gal alpha-2,3-Sialyltransferase 2/ST3GAL2 Protein - H00006483-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

Recombinant Human ST3GAL2, CF - 7275-GT-020 from R&D Systems

Category Protein
Source Chinese Hamster Ovary cell line, CHO-derived, Pro52-Gln350, with an N-terminal CD33 signal and a C-terminal 6-His tag

ST3GAL2 Blocking Peptide - 33R-1106 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

ST3GAL2 - H00006483-P01-02 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Source in vitro transl.
Species Human

ST3GAL2 - H00006483-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

ST3GAL2 - H00006483-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

SIAT4B Recombinant Protein - 96-706 from ProSci

Category Protein
Source HEK293 cells
Species Human
The purity of rh ST3GAL2 / SIAT4B was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

ST3GAL2 fusion protein - ag4528 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

ST3GAL2 fusion protein - ag4721 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human ST3GAL2, His-tagged - ST3GAL2-576H from Creative Biomart

Category Protein
Source CHO Cells
Species Human

Recombinant Human CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltra - CSB-YP618099HU CSB-EP618099HU CSB-BP618099HU CSB-MP618099HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant Human ST3GAL2 Protein, CF - 7275-GT from R&D Systems

Category Protein
Prices $359.00
Sizes 20 µg
Source Chinese Hamster Ovary cell line, CHO-derived Pro52-Gln350, with an N-terminal CD33 signal and a C-terminal 6-His tag
Species Human

Human ST3GAL2 Protein - ST2-H5228 from ACROBiosystems

Category Protein
Prices $290.00, $1,800.00
Sizes 50 µg, 1 mg (200ug x 5)
Source Recombinant Human ST3GAL2 /SIAT4B Protein (rh ST3GAL2 / SIAT4B) Pro 52 - Gln 350 (Accession # AAH36777) was produced in human 293 cells (HEK293) at ACRObiosystems.
Species Human

ST3 beta-Gal alpha-2,3-Sialyltransferase 2/ST3GAL2 Protein - NBP1-87044PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

Human ST3GAL2 protein - orb257856 from Biorbyt

Category Protein
Species Human

ST3GAL2-Blocking-Peptide-N-term - BP21060a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

ST3GAL2 Peptide, Human - M34GP15234H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 (ST3GAL2), Recombinant Protein - MBS1465660 from MyBioSource

Category Protein
Prices $1,115.00, $1,115.00, $1,345.00, $1,345.00, $1,765.00, $1,765.00, $2,230.00, $2,230.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 (ST3GAL2), Recombinant Protein - MBS1401787 from MyBioSource

Category Protein
Prices $1,115.00, $1,115.00, $1,345.00, $1,345.00, $1,765.00, $1,765.00, $2,230.00, $2,230.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Chimpanzee

Recombinant Human ST3GAL2 Protein, CF - 7275-GT from Novus Biologicals

Category Protein
Prices $359.00
Sizes 20 µg
Species Human
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