ST3GAL2

Gene Symbol	ST3GAL2
Entrez Gene	6483
Alt Symbol	Gal-NAc6S, SIAT4B, ST3GALII, ST3GalA.2
Species	Human
Gene Type	protein-coding
Description	ST3 beta-galactoside alpha-2,3-sialyltransferase 2
Other Description	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2\|Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase\|SIAT4-B\|ST3Gal II\|alpha 2,3-ST 2\|beta-galactoside alpha-2,3-sialyltransferase 2\|beta-galactoside alpha-2,3-sialytransferase\|sialyltransferase 4B (beta-galactosidase alpha-2,3-sialytransferase)
Swissprots	O00654 Q16842
Accessions	CAS91689 EAW51818 EAW51819 EAW51820 EAW51821 Q16842 AF086257 AI933719 AK127322 BAG54481 AK313020 BAG35855 BC036777 AAH36777 BC064480 BI832366 JF432706 ADZ15923 U63090 AAB40389 X96667 CAA65447 NM_006927 NP_008858
Function	It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found in terminal carbohydrate groups of certain glycoproteins, oligosaccharides and glycolipids. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values.
Subcellular Location	Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Secreted {ECO:0000250}. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid (By similarity). {ECO:0000250}.
Tissue Specificity	Highly expressed in skeletal muscle and heart and to a much lesser extent in brain, placenta, liver and pancreas. Scarcely detectable in lung and kidney. {ECO:0000269\|PubMed:8920913, ECO:0000269\|PubMed:9266697}.
Top Pathways	Mucin type O-Glycan biosynthesis, Glycosaminoglycan biosynthesis - keratan sulfate, Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - ganglio series

St3Gal-II (H-150) - sc-292044 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

St3Gal-II (H-150): sc-292044. Western blot analysis of St3Gal-II expression in K-562 (A) and Jurkat (C) whole cell lysates and human liver tissue extract (B).

St3Gal-II (G-15) - sc-165600 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

St3Gal-II (34-K) - sc-100856 from Santa Cruz Biotechnology

Prices	$295.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

St3Gal-II (34-K): sc-100856. Western blot analysis of St3Gal-II expression in non-transfected 293T: sc-117752 (A), human St3Gal-I transfected 293T: sc-115398 (B) and K-562 (C) whole cell lysates.

Anti-ST3GAL2 antibody - ab96028 from Abcam

Prices	$359.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-ST3GAL2 antibody (ab96028) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

Anti-ST3GAL2 antibody - ab72618 from Abcam

Prices	$359.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-ST3GAL2 antibody (ab72618) at 1/500 dilutionLane 1 : ST3GAL2 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilutiondeveloped using the ECL technique

Anti-ST3GAL2 Antibody (aa68-327) - LS-C185577 from LifeSpan Bioscience

Prices	$335.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

IHC of paraffin-embedded SW480 xenograft using ST3GAL2 antibody at 1:100 dilution.

Anti-ST3GAL2 Antibody (C-Terminus) IHC-plus™ - LS-B11026 from LifeSpan Bioscience

Prices	$450.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-ST3GAL2 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11026 concentration 10 ug/ml.

Anti-ST3GAL2 Antibody (clone 1E12) - LS-C133437 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	1E12

ST3GAL2 monoclonal antibody (M01), clone 1E12 Western blot of ST3GAL2 expression in K-562.

Anti-ST3GAL2 Antibody (aa28-128, Azide-free) - LS-C328605 from LifeSpan Bioscience

Host	Mouse
Clonality	Monoclonal

ST3 beta-Gal alpha-2,3-Sialyltransferase 2/ST3GAL2 Antibody - AF7275 from Novus Biologicals

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Sheep
Clonality	Polyclonal

Western blot shows lysates of human heart tissue, mouse heart tissue, and rat heart tissue. PVDF membrane was probed with 0.5 µg/mL of Sheep Anti-Human ST3 beta -Gal alpha -2,3-Sialyltransferase 2/ST3GAL2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7275) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for ST3 beta -Gal alpha -2,3-Sialyltransferase 2/ST3GAL2 at approximately 40 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

ST3 beta-Gal alpha-2,3-Sialyltransferase 2/ST3GAL2 Antibody - NBP1-87044 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry-Paraffin: ST3GAL2 Antibody [NBP1-87044] - Staining of human hippocampus shows strong cytoplasmic positivity in neuronal cells.

ST3 beta-Gal alpha-2,3-Sialyltransferase 2/ST3GAL2 Antibody (1E12.) - H00006483-M01 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	1E12.

Western Blot: ST3 beta-Gal alpha-2,3-Sialyltransferase 2/ST3GAL2 Antibody (1E12) [H00006483-M01] - ST3GAL2 monoclonal antibody (M01), clone 1E12 Analysis of ST3GAL2 expression in K-562.

ST3 beta-Gal alpha-2,3-Sialyltransferase 2/ST3GAL2 Antibody - NBP1-69570 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: ST3GAL2 Antibody [NBP1-69570] - This Anti-ST3GAL2 antibody was used in Western Blot of Fetal Heart tissue lysate at a concentration of 1ug/ml.

ST3 beta-Gal alpha-2,3-Sialyltransferase 2/ST3GAL2 Antibody - NBP1-32451 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

ST3 beta-Gal alpha-2,3-Sialyltransferase 2/ST3GAL2 Antibody - H00006483-B01P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Western Blot: ST3 beta-Gal alpha-2,3-Sialyltransferase 2/ST3GAL2 Antibody [H00006483-B01P] - Analysis of ST3GAL2 expression in transfected 293T cell line by ST3GAL2 polyclonal antibody. Lane 1: ST3GAL2 transfected lysate(38.5 KDa). Lane 2: Non-transfected lysate.

ST3 beta-Gal alpha-2,3-Sialyltransferase 2/ST3GAL2 Antibody - H00006483-D01P from Novus Biologicals

Prices	$399.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western Blot: ST3 beta-Gal alpha-2,3-Sialyltransferase 2/ST3GAL2 Antibody [H00006483-D01P] - Analysis of ST3GAL2 expression in human kidney.

Anti-ST3GAL2 antibody produced in rabbit - HPA017270 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-ST3GAL2: <B>Cat. No. HPA017270</B>: Immunohistochemical staining of human hippocampus shows strong cytoplasmic positivity in neuronal cells.

Anti-ST3GAL2 antibody produced in rabbit - AV46800 from Sigma-Aldrich

Prices	$347.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Cell Type: fetal heart (<B>Cat. No. AV46800</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1.0 μg/mL in cell type fetal heart

Anti-ST3GAL2 antibody produced in mouse - SAB1406439 from Sigma-Aldrich

Prices	$347.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-ST3GAL2: <B>Cat. No. SAB1406439</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~38.5 kDa using ST3GAL2 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-ST3GAL2 antibody produced in rabbit - SAB1411275 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-ST3GAL2: <B>Cat. No. SAB1411275</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~40.2 kDa using human kidney lysate.

Monoclonal Anti-ST3GAL2 antibody produced in mouse - WH0006483M1 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	1E12

<B>Immunoblotting</B><BR/>Monoclonal Anti-ST3GAL2, <B>Cat. No. WH0006483M1</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~40.1 kDa using K-562 lysate.

ST3GAL2 antibody - C-terminal region (ARP46800_P050) - ARP46800_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

ST3GAL2-Antibody-monoclonal-M01 - AT4051a from Abgent, a WuXi AppTec company

Prices	$315.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	1E13

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .

ST3GAL2-Antibody-N-term - AP21060a from Abgent, a WuXi AppTec company

Prices	$99.00, $295.00
Sizes	80 µl, 400 µl
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of lysates from human heart and human kidney tissue (from left to right), using ST3GAL2 Antibody (Nterm)(Cat. #AP21060a). AP21060a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

Human/Mouse/Rat ST3 beta -Gal alpha -2,3-Sialyltransferase 2/ST3GAL2 Antibody - AF7275 from R&D Systems

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Sheep

Detection of Human, Mouse, and Rat ST3 beta -Gal a-2,3-Sialyltransferase 2/ST3GAL2 by Western Blot. Western blot shows lysates of human heart tissue, mouse heart tissue, and rat heart tissue. PVDF membrane was probed with 0.5 µg/mL of Sheep Anti-Human ST3 beta -Gal a-2,3-Sialyltransferase 2/ST3GAL2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7275) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016 ). A specific band was detected for ST3 beta -Gal a-2,3-Sialyltransferase 2/ST3GAL2 at approximately 40 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1 .

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