Gene Symbol | CCL25 |
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Entrez Gene | 6370 |
Alt Symbol | Ckb15, SCYA25, TECK |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) ligand 25 |
Other Description | C-C motif chemokine 25|Ck beta-15|TECKvar|chemokine TECK|small inducible cytokine subfamily A (Cys-Cys), member 25|small-inducible cytokine A25|thymus expressed chemokine|thymus-expressed chemokine |
Swissprots | A6NI52 A1L4J4 Q96KJ7 B5MCA5 O15444 A8K9E7 |
Accessions | EAW68951 EAW68952 O15444 AB046579 BAB62257 AI313430 AI961745 AK292662 BAF85351 BC125136 AAI25137 BC130561 AAI30562 BC144463 AAI44464 HQ258070 ADR82824 U86358 AAB69981 XM_011528177 XP_011526479 NM_001201359 NP_001188288 NM_005624 NP_005615 NM_148888 |
Function | Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
Subcellular Location | Secreted. |
Tissue Specificity | Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine. |
Top Pathways | Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Chemokine signaling pathway |
TECK (K-16) - sc-12277 from Santa Cruz Biotechnology
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TECK (A-20) - sc-12276 from Santa Cruz Biotechnology
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TECK (500-M48) - sc-65377 from Santa Cruz Biotechnology
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Anti-TECK antibody - ab2164 from Abcam
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Anti-TECK antibody - ab124071 from Abcam
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Anti-TECK antibody - ab188159 from Abcam
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Anti-TECK antibody - ab625 from Abcam
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Anti-TECK antibody (Biotin) - ab83146 from Abcam
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Anti-TECK antibody [EPR12388(2)] - ab200343 from Abcam
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Anti-TECK antibody [MM0150-9G99] - ab89541 from Abcam
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Anti-CCL25 / TECK Antibody - LS-C18050 from LifeSpan Bioscience
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Anti-CCL25 / TECK Antibody (clone 89827) - LS-C150161 from LifeSpan Bioscience
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Anti-CCL25 / TECK Antibody (aa65-95, FITC) - LS-C213106 from LifeSpan Bioscience
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Anti-CCL25 / TECK Antibody (Biotin) - LS-C104509 from LifeSpan Bioscience
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Anti-CCL25 / TECK Antibody - LS-C104428 from LifeSpan Bioscience
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Anti-CCL25 / TECK Antibody (aa65-95, APC) - LS-C213104 from LifeSpan Bioscience
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Anti-CCL25 / TECK Antibody (aa65-95, Azide-free, HRP) - LS-C213108 from LifeSpan Bioscience
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Anti-CCL25 / TECK Antibody (aa65-95, AP) - LS-C213107 from LifeSpan Bioscience
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Anti-CCL25 / TECK Antibody (aa65-95, PE) - LS-C213109 from LifeSpan Bioscience
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Anti-CCL25 / TECK Antibody (aa24-150, Biotin) - LS-C298429 from LifeSpan Bioscience
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Anti-CCL25 / TECK Antibody (aa24-150, FITC) - LS-C305277 from LifeSpan Bioscience
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Anti-CCL25 / TECK Antibody - LS-C285684 from LifeSpan Bioscience
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Anti-CCL25 / TECK Antibody (HRP) - LS-C316985 from LifeSpan Bioscience
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Anti-CCL25 / TECK Antibody (FITC) - LS-C316981 from LifeSpan Bioscience
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Anti-CCL25 / TECK Antibody (aa65-95) - LS-C329328 from LifeSpan Bioscience
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