IFNAR1

Gene Symbol	IFNAR1
Entrez Gene	3454
Alt Symbol	AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC
Species	Human
Gene Type	protein-coding
Description	interferon (alpha, beta and omega) receptor 1
Other Description	CRF2-1|IFN-R-1|IFN-alpha/beta receptor 1|alpha-type antiviral protein|beta-type antiviral protein|cytokine receptor class-II member 1|cytokine receptor family 2 member 1|interferon alpha/beta receptor 1|interferon-alpha/beta receptor alpha chain|interferon-beta receptor 1|type I interferon receptor 1
Swissprots	Q6PKD7 Q53GW9 B4DNT3 Q8WTZ2 B2R6L9 D3DSF0 P17181 Q53H11 Q7M4L2
Accessions	AAT49100 CAA42992 EAX09837 EAX09838 EAX09839 P17181 AK123813 AK222770 BAD96490 AK222812 BAD96532 AK298051 BAG60345 AK312631 BAG35516 BC002590 AAH02590 BC014338 BC021825 AAH21825 BC035603 BC065751 BG116121 BG548299 BX537636 CA309858 DQ891323 ABM82249 DQ894507 ABM85433 J03171 AAA52730 R15745 XM_005260964 XP_005261021 XM_011529552 XP_011527854 NM_000629 NP_000620
Function	Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta- subunits themselves. Can also transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
Subcellular Location	Isoform 1: Membrane; Single-pass type I membrane protein.
Tissue Specificity	IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. {ECO:0000269|PubMed:8307198}.
Top Pathways	Osteoclast differentiation, PI3K-Akt signaling pathway, Herpes simplex infection, Influenza A, Measles

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse IFNAR1 ELISA Pair Set - orb145961 from Biorbyt Category ELISA Kit Prices $646.00, $1,369.00 Sizes 5 plates, 15 plates

Interferon alpha/beta receptor 1 (IFNAR1), Human, ELISA Kit - E01I0427 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Interferon alpha/beta receptor 1, IFNAR1, Human, ELISA Kit - E1425h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

IFNAR1 (Human) Matched Antibody Pair - H00003454-AP11 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Custom Human IFN-alpha/beta R1 ELISA - ELH-IFNabR1 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Interferon alpha/beta receptor 1, ELISA Kit - MBS281658 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon alpha/beta receptor 1 (IFNAR1), ELISA Kit - MBS7231513 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/ml

Interferon alpha/beta receptor 1 (IFNAR1), ELISA Kit - MBS7217466 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon alpha/beta receptor 1 (IFNAR1), ELISA Kit - MBS7218234 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse IFNAR1 ELISA Pair Set - SEK50469-5 from Sino Biological Category ELISA Kit Prices $350.00, $350.00 Sizes 5 plates, 15 plates

Human IFNAR1 / IFNAR ELISA Pair Set - SEK13222-5 from Sino Biological Category ELISA Kit Prices $350.00, $350.00 Sizes 5 plates, 15 plates

Bovine IFNAR1 / IFNAR ELISA Kit (Custom ELISA) - LS-F17212 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Pig IFNAR1 / IFNAR ELISA Kit (Custom ELISA) - LS-F17213 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Mouse IFNAR1 / IFNAR ELISA Kit (Custom ELISA) - LS-F17210 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Human IFNAR1 / IFNAR ELISA Kit (Sandwich ELISA) - LS-F17211 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Interferon alpha/beta receptor 1 (IFNAR1), ELISA Kit - MBS7249794 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon alpha/beta receptor 1 (IFNAR1), ELISA Kit - MBS7218507 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon alpha/beta receptor 1 (IFNAR1), ELISA Kit - MBS7234655 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Interferon alpha/beta receptor 1 (IFNAR1), ELISA Kit - MBS7233346 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon alpha/beta receptor 1 (IFNAR1), ELISA Kit - MBS7219077 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Interferon alpha/beta receptor 1 ELISA Kit - abx250876 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

Human IFNAR1/IFNAR ELISA Kit - NS-E10224 from Novatein Biosciences Category ELISA Kit Prices $459.00 Sizes 96 t Sensitivity 60 pg/mL Range 62.5 - 4000 pg/ml

Human IFN-alpha/beta R1 ELISA - RAB1511 from Sigma-Aldrich Prices $615.00 Sizes 1 kt

Human Interferon alpha/beta receptor 1 ELISA Kit - EKE53901 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.034 ng/mL Range 0.156-10 ng/mL

IFNAR1 - EKH3172 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156-10ng/ml

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