PKDCC

Gene Symbol	PKDCC
Entrez Gene	91461
Alt Symbol	SGK493, Vlk
Species	Human
Gene Type	protein-coding
Description	protein kinase domain containing, cytoplasmic
Other Description	extracellular tyrosine-protein kinase PKDCC|protein kinase domain containing, cytoplasmic homolog|protein kinase domain-containing protein, cytoplasmic|protein kinase-like protein SgK493|sugen kinase 493|vertebrate lonesome kinase
Swissprots	Q96I09 D6W5A0 Q504Y2
Accessions	EAX00325 EAX00326 Q504Y2 AK311155 BC007901 AAH07901 BC062988 AAH62988 BC094697 AAH94697 BC110513 AAI10514 BC110514 AAI10515 BM738316 BQ013425 CF131963 DB231841 DB457034 NM_138370 NP_612379
Function	Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylation of MMP1, MMP13, MMP14, MMP19 and ERP29 (PubMed:25171405). Probably plays a role in platelets: rapidly and quantitatively secreted from platelets in response to stimulation of platelet degranulation (PubMed:25171405). May also have serine/threonine protein kinase activity. Required for longitudinal bone growth through regulation of chondrocyte differentiation. May be indirectly involved in protein transport from the Golgi apparatus to the plasma membrane (By similarity). {ECO:0000250|UniProtKB:Q5RJI4, ECO:0000269|PubMed:25171405}.
Subcellular Location	Secreted {ECO:0000269|PubMed:25171405}. Golgi apparatus {ECO:0000250|UniProtKB:Q5RJI4}.
Tissue Specificity	Highly expressed in platelets. {ECO:0000269|PubMed:25171405}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Protein kinase-like protein SgK493 full length protein - ab164858 from Abcam Category Protein Source Wheat germ Species Human

Human Protein kinase-like protein SgK493 protein fragment - ab131683 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

PKDCC / SGK493 Antibody Blocking Peptide - LS-E30842 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human Protein kinase-like protein SgK493 Protein - H00091461-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PKDCC - H00091461-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PKDCC - H00091461-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SGK493 fusion protein - ag16428 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

VLK protein-GST fusion - 009-001-U57 from Rockland Immunochemicals Inc Category Protein Prices $499.00 Sizes 50 µg Species Human

VLK protein-GST fusion - 009-001-U57S from Rockland Immunochemicals Inc Category Protein Prices $265.00 Sizes 20 µg Species Human

Recombinant Human Protein kinase domain-containing protein, cytoplasmic(PKDCC) - CSB-YP684345HU CSB-EP684345HU CSB-BP684345HU CSB-MP684345HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

VLK, Recombinant Protein - MBS515268 from MyBioSource Category Protein Prices $260.00, $415.00 Sizes 20 µg, 50 µg Source Sf9 insect cells using baculovirus Species Human

Protein kinase-like protein SgK493 Recombinant Protein Antigen - NBP1-80758PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Protein kinase-like protein SgK493 Recombinant Protein Antigen - NBP1-80757PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Protein kinase-like protein SgK493 Protein - NBP1-80756PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

PKDCC Peptide, Human - M34GP11841H from Creative Peptides Category Peptide Source Synthetic. Species Human

Protein kinase domain-containing protein, cytoplasmic (PKDCC), Recombinant Protein - MBS1307834 from MyBioSource Category Protein Prices $1,280.00, $1,280.00, $1,500.00, $1,500.00, $2,095.00, $2,095.00, $2,560.00, $2,560.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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