PKDCC

Gene Symbol PKDCC
Entrez Gene 91461
Alt Symbol SGK493, Vlk
Species Human
Gene Type protein-coding
Description protein kinase domain containing, cytoplasmic
Other Description extracellular tyrosine-protein kinase PKDCC|protein kinase domain containing, cytoplasmic homolog|protein kinase domain-containing protein, cytoplasmic|protein kinase-like protein SgK493|sugen kinase 493|vertebrate lonesome kinase
Swissprots Q96I09 D6W5A0 Q504Y2
Accessions EAX00325 EAX00326 Q504Y2 AK311155 BC007901 AAH07901 BC062988 AAH62988 BC094697 AAH94697 BC110513 AAI10514 BC110514 AAI10515 BM738316 BQ013425 CF131963 DB231841 DB457034 NM_138370 NP_612379
Function Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylation of MMP1, MMP13, MMP14, MMP19 and ERP29 (PubMed:25171405). Probably plays a role in platelets: rapidly and quantitatively secreted from platelets in response to stimulation of platelet degranulation (PubMed:25171405). May also have serine/threonine protein kinase activity. Required for longitudinal bone growth through regulation of chondrocyte differentiation. May be indirectly involved in protein transport from the Golgi apparatus to the plasma membrane (By similarity). {ECO:0000250|UniProtKB:Q5RJI4, ECO:0000269|PubMed:25171405}.
Subcellular Location Secreted {ECO:0000269|PubMed:25171405}. Golgi apparatus {ECO:0000250|UniProtKB:Q5RJI4}.
Tissue Specificity Highly expressed in platelets. {ECO:0000269|PubMed:25171405}.

PKDCC CRISPR/Cas9 KO Plasmid (h) - sc-410480 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PKDCC HDR Plasmid (h) - sc-410480-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PKDCC Double Nickase Plasmid (h) - sc-410480-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PKDCC Double Nickase Plasmid (h2) - sc-410480-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PKDCC CRISPR Activation Plasmid (h) - sc-410480-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PKDCC CRISPR Activation Plasmid (h2) - sc-410480-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PKDCC Lentiviral Activation Particles (h) - sc-410480-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PKDCC Lentiviral Activation Particles (h2) - sc-410480-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PKDCC siRNA (h) - sc-94454 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PKDCC shRNA Plasmid (h) - sc-94454-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PKDCC shRNA (h) Lentiviral Particles - sc-94454-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU004031 from Sigma-Aldrich

Category siRNA

MISSION® siRNA - SIHK2078 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2076 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2077 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN16860 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16860 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PKDCC siRNA (Human) - CRJ4043 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PKDCC (NM_138370.2) - SHH376424 from Creative biogene

Category siRNA
Species Reactivities Human

Human PKDCC siRNA - orb274544 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PKDCC shRNA Plasmid (Human) - CHJ4043 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PKDCC miRNA 3'UTR clone - MiUTR3H-13152 from Creative biogene

Species Reactivities Human
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