INSC

Gene Symbol INSC
Entrez Gene 387755
Alt Symbol -
Species Human
Gene Type protein-coding
Description inscuteable homolog (Drosophila)
Other Description inscuteable spindle orientation adaptor protein|protein inscuteable homolog
Swissprots Q4AC97 A0PJX5 Q4AC96 Q3C1V6 Q4AC98 Q1MX18 Q4AC95 Q1MX19
Accessions Q1MX18 AB231744 BAE46891 AB231745 BAE17133 AB231746 BAE17134 AB231747 BAE17135 AB231748 BAE17136 AB231749 BAE46892 AB236158 BAE93463 AB236159 BAE93464 BC117561 BC127700 AAI27701 BC156332 AAI56333 BC157083 AAI57084 BU147420 DY654442 XM_006718227 XP_006718290 XM_011520082 XP_011518384 XM_011520083 XP_011518385 XM_011520084 XP_011518386 XM_011520085 XP_011518387 XM_011520086 XP_011518388 XM_011520087 XP_011518389 XM_011520088 XP_011518390 XR_930868 NM_001031853 NP_001027024 NM_001042536 NP_001036001 NM_001278313 NP_001265242 NM_001278314 NP_001265243 NM_001278315 NP_001265244 NM_001278316 NP_001265245
Function May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis it may regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium. {ECO:0000269|PubMed:16458856}.
Subcellular Location Cytoplasm. Note=Localizes to the apical cortex of mitotic epidermal cells and to the apical side of neuronal progenitor cells. {ECO:0000250}.
Tissue Specificity Isoform 1 is expressed in various tissues with stronger expression in liver, kidney and small intestine. Isoform 2 is abundantly expressed in small intestine and to a lower extent in lung and pancreas. {ECO:0000269|PubMed:12469229, ECO:0000269|PubMed:16458856}.

INSC Antibody Blocking Peptide - LS-E10271 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

INSC Antibody Blocking Peptide - LS-E10272 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

INSC-Antibody-Center-Blocking-Peptide - BP9702c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

INSC-Antibody-C-term-Blocking-Peptide - BP9702b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human Protein inscuteable homolog(INSC) - CSB-YP634907HU CSB-EP634907HU CSB-BP634907HU CSB-MP634907HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

INSC Protein - NBP1-90980PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

INSC Peptide, Human - M34GP07671H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Protein inscuteable homolog (INSC), Recombinant Protein - MBS1304291 from MyBioSource

Category Protein
Prices $1,380.00, $1,380.00, $1,595.00, $1,595.00, $2,295.00, $2,295.00, $2,760.00, $2,760.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
Search more