| Gene Symbol |
IRAK3
|
| Entrez Gene |
11213
|
| Alt Symbol |
ASRT5, IRAKM
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
interleukin-1 receptor-associated kinase 3
|
| Other Description |
IL-1 receptor-associated kinase M
|
| Swissprots |
B4DQ57 Q9Y616
|
| Accessions |
EAW97164 Q9Y616 AF113136 AAD40879 AK023663 AK298645 BAG60819 AK314040 BAG36749 AL049435 BC029493 BC047399 BC057800 AAH57800 BC069388 AAH69388 BP292474 BQ009433 DA594800 JF432379 ADZ15596 NM_001142523 NP_001135995 NM_007199 NP_009130
|
| Function |
Inhibits dissociation of IRAK1 and IRAK4 from the Toll- like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex. {ECO:0000250|UniProtKB:Q8K4B2}.
|
| Tissue Specificity |
Expressed predominantly in peripheral blood lymphocytes. {ECO:0000269|PubMed:10383454}.
|
| Top Pathways |
Apoptosis, Neurotrophin signaling pathway
|