Gene Symbol | IRAK3 |
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Entrez Gene | 11213 |
Alt Symbol | ASRT5, IRAKM |
Species | Human |
Gene Type | protein-coding |
Description | interleukin-1 receptor-associated kinase 3 |
Other Description | IL-1 receptor-associated kinase M |
Swissprots | B4DQ57 Q9Y616 |
Accessions | EAW97164 Q9Y616 AF113136 AAD40879 AK023663 AK298645 BAG60819 AK314040 BAG36749 AL049435 BC029493 BC047399 BC057800 AAH57800 BC069388 AAH69388 BP292474 BQ009433 DA594800 JF432379 ADZ15596 NM_001142523 NP_001135995 NM_007199 NP_009130 |
Function | Inhibits dissociation of IRAK1 and IRAK4 from the Toll- like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex. {ECO:0000250|UniProtKB:Q8K4B2}. |
Tissue Specificity | Expressed predominantly in peripheral blood lymphocytes. {ECO:0000269|PubMed:10383454}. |
Top Pathways | Apoptosis, Neurotrophin signaling pathway |
Human IRAKM full length protein - ab125546 from Abcam
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Human IRAKM full length protein - ab153169 from Abcam
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Human IRAKM protein fragment - ab153170 from Abcam
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IRAKM peptide - ab6231 from Abcam
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IRAK3 / IRAKM / IRAK-M Antibody Blocking Peptide - LS-E3123 from LifeSpan Bioscience
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IRAK3 / IRAKM / IRAK-M Antibody Blocking Peptide - LS-E14914 from LifeSpan Bioscience
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IRAK3 / IRAKM / IRAK-M Antibody Blocking Peptide - LS-E9275 from LifeSpan Bioscience
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IRAK3 / IRAKM / IRAK-M Antibody Blocking Peptide - LS-E29953 from LifeSpan Bioscience
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IRAK3 / IRAKM / IRAK-M Antibody Blocking Peptide - LS-E26773 from LifeSpan Bioscience
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Recombinant Human IRAK3 Protein - H00011213-Q01 from Novus Biologicals
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Recombinant Human IRAK3 Protein - H00011213-P01 from Novus Biologicals
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IRAK3 Blocking Peptide - NBP1-76782PEP from Novus Biologicals
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IRAK3 Peptide - P2807 from Novus Biologicals
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IRAK3-Antibody-N-term-Blocking-Peptide - BP7804a from Abgent, a WuXi AppTec company
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IRAK3 peptide - GTX26231 from GeneTex
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IRAK3 Blocking Peptide - 33R-6900 from Fitzgerald
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Human IRAK3 Protein - abx067410 from Abbexa
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IRAK3 - H00011213-P01-10 from Acris Antibodies
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IRAK3 - H00011213-P01-25 from Acris Antibodies
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IRAK3 - H00011213-Q01-10 from Acris Antibodies
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IRAK3 - H00011213-Q01-25 from Acris Antibodies
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IRAK3 Control Peptide - AP30443CP-N from Acris Antibodies
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Interleukin 1 Receptor Associated Kinase 3 (IRAK3), Human - 20-7803 from ARP American Research Products
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IRAK-M Peptide - 2355P from ProSci
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IRAK3 fusion protein - ag4959 from Proteintech Group
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