IRAK3

Gene Symbol	IRAK3
Entrez Gene	11213
Alt Symbol	ASRT5, IRAKM
Species	Human
Gene Type	protein-coding
Description	interleukin-1 receptor-associated kinase 3
Other Description	IL-1 receptor-associated kinase M
Swissprots	B4DQ57 Q9Y616
Accessions	EAW97164 Q9Y616 AF113136 AAD40879 AK023663 AK298645 BAG60819 AK314040 BAG36749 AL049435 BC029493 BC047399 BC057800 AAH57800 BC069388 AAH69388 BP292474 BQ009433 DA594800 JF432379 ADZ15596 NM_001142523 NP_001135995 NM_007199 NP_009130
Function	Inhibits dissociation of IRAK1 and IRAK4 from the Toll- like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex. {ECO:0000250|UniProtKB:Q8K4B2}.
Tissue Specificity	Expressed predominantly in peripheral blood lymphocytes. {ECO:0000269|PubMed:10383454}.
Top Pathways	Apoptosis, Neurotrophin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IRAK-M CRISPR/Cas9 KO Plasmid (h) - sc-403219 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IRAK-M HDR Plasmid (h) - sc-403219-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IRAK-M Double Nickase Plasmid (h) - sc-403219-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IRAK-M Double Nickase Plasmid (h2) - sc-403219-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IRAK-M CRISPR Activation Plasmid (h) - sc-403219-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IRAK-M CRISPR Activation Plasmid (h2) - sc-403219-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IRAK-M Lentiviral Activation Particles (h) - sc-403219-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IRAK-M Lentiviral Activation Particles (h2) - sc-403219-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IRAK-M siRNA (h) - sc-39098 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

IRAK-M shRNA Plasmid (h) - sc-39098-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

IRAK-M shRNA (h) Lentiviral Particles - sc-39098-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

IRAK3 RNAi - H00011213-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

IRAK3 RNAi - H00011213-R03 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU053111 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK0980 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0979 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0981 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN2366 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2366 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03919 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr03919

IRAK3 siRNA (Human) - CRH7682 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

IRAK3 - MBS8208462 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

IRAK-M CRISPR/Cas9 KO Plasmid (h2) - sc-403219-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IRAK-M HDR Plasmid (h2) - sc-403219-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human IRAK3 (NM_007199.2) - SHH320521 from Creative biogene Category siRNA Species Reactivities Human

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