Gene Symbol | IRAK3 |
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Entrez Gene | 11213 |
Alt Symbol | ASRT5, IRAKM |
Species | Human |
Gene Type | protein-coding |
Description | interleukin-1 receptor-associated kinase 3 |
Other Description | IL-1 receptor-associated kinase M |
Swissprots | B4DQ57 Q9Y616 |
Accessions | EAW97164 Q9Y616 AF113136 AAD40879 AK023663 AK298645 BAG60819 AK314040 BAG36749 AL049435 BC029493 BC047399 BC057800 AAH57800 BC069388 AAH69388 BP292474 BQ009433 DA594800 JF432379 ADZ15596 NM_001142523 NP_001135995 NM_007199 NP_009130 |
Function | Inhibits dissociation of IRAK1 and IRAK4 from the Toll- like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex. {ECO:0000250|UniProtKB:Q8K4B2}. |
Tissue Specificity | Expressed predominantly in peripheral blood lymphocytes. {ECO:0000269|PubMed:10383454}. |
Top Pathways | Apoptosis, Neurotrophin signaling pathway |
IRAK-M Antibody - 4369 from Cell Signaling Technology
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IRAK-M (C-20) - sc-23656 from Santa Cruz Biotechnology
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IRAK-M (H-150) - sc-366015 from Santa Cruz Biotechnology
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IRAK-M (N-20) - sc-23654 from Santa Cruz Biotechnology
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IRAK-M (XX-6) - sc-100389 from Santa Cruz Biotechnology
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Anti-IRAKM antibody - ab77216 from Abcam
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Anti-IRAKM antibody - ab97518 from Abcam
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Anti-IRAKM antibody - ab37809 from Abcam
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Anti-IRAKM antibody - ab56880 from Abcam
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Anti-IRAKM antibody - ab56884 from Abcam
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Anti-IRAKM antibody [Y278] - ab32394 from Abcam
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Anti-IRAKM antibody - C-terminal - ab189128 from Abcam
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Anti-IRAKM antibody - C-terminal - ab71669 from Abcam
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Anti-IRAKM antibody - Carboxyterminal end - ab8116 from Abcam
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Anti-IRAK3 / IRAKM / IRAK-M Antibody (C-Terminus) - LS-C89429 from LifeSpan Bioscience
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Anti-IRAK3 / IRAKM / IRAK-M Antibody (aa441-490) - LS-C30307 from LifeSpan Bioscience
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Anti-IRAK3 / IRAKM / IRAK-M Antibody (C-Terminus, clone Y278) - LS-C49541 from LifeSpan Bioscience
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Anti-IRAK3 / IRAKM / IRAK-M Antibody (aa581-596) - LS-C121240 from LifeSpan Bioscience
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Anti-IRAK3 / IRAKM / IRAK-M Antibody (C-Terminus) - LS-C209752 from LifeSpan Bioscience
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Anti-IRAK3 / IRAKM / IRAK-M Antibody (C-Terminus) - LS-C209753 from LifeSpan Bioscience
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Anti-IRAK3 / IRAKM / IRAK-M Antibody (aa516-544, APC) - LS-C236638 from LifeSpan Bioscience
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Anti-IRAK3 / IRAKM / IRAK-M Antibody (aa516-544, AP) - LS-C236639 from LifeSpan Bioscience
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Anti-IRAK3 / IRAKM / IRAK-M Antibody (aa516-544, FITC) - LS-C236640 from LifeSpan Bioscience
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Anti-IRAK3 / IRAKM / IRAK-M Antibody (aa516-544, Biotin) - LS-C236641 from LifeSpan Bioscience
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Anti-IRAK3 / IRAKM / IRAK-M Antibody (aa516-544, PE) - LS-C236642 from LifeSpan Bioscience
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