IGF2BP2

Gene Symbol	IGF2BP2
Entrez Gene	10644
Alt Symbol	IMP-2, IMP2, VICKZ2
Species	Human
Gene Type	protein-coding
Description	insulin-like growth factor 2 mRNA binding protein 2
Other Description	IGF-II mRNA-binding protein 2|IGF2 mRNA-binding protein 2|VICKZ family member 2|insulin-like growth factor 2 mRNA-binding protein 2
Swissprots	B3FTN3 A0A4Z0 B3FTN4 B3FTN2 Q9Y6M1
Accessions	CAY39325 EAW78209 EAW78210 EAW78211 Q9Y6M1 AA451676 AF117107 AAD09827 AI336648 AI348863 AK290664 BAF83353 AK296703 BAG59297 AK309611 AW193691 BC021290 AAH21290 BX537583 CD110066 DQ892161 ABM83087 EU176689 ABW03490 EU408701 ACB86625 EU408702 ACB86626 EU408703 ACB86627 EU408704 ACB86628 XM_006713477 XP_006713540 XM_006713478 XP_006713541 XM_011512337 XP_011510639 XM_011512338 XP_011510640 XM_011512339 XP_011510641 XM_011512340 XP_011510642 XM_011512341 XP_011510643 XM_011512342 XP_011510644 XR_427358 NM_001007225 NP_001007226 NM_001291869 NP_001278798 NM_001291872 NP_001278801 NM_001291873 NP_001278802 NM_001291874 NP_001278803 NM_001291875 NP_001278804 NM_006548 NP_006539
Function	RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation (By similarity). Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. Binds to beta- actin/ACTB and MYC transcripts. {ECO:0000250, ECO:0000269|PubMed:23640942, ECO:0000269|PubMed:9891060}.
Subcellular Location	Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Localizes at the connecting piece and the tail of the spermatozoa. In response to cellular stress, such as oxidative stress, recruited to stress granules.
Tissue Specificity	Expressed in oocytes, granulosa cells of small and growing follicles, Leydig cells, spermatogonia and semen (at protein level). Expressed in testicular cancer (at protein level). Expressed weakly in heart, placenta, skeletal muscle, bone marrow, colon, kidney, salivary glands, testis and pancreas. Detected in fetal liver, fetal ovary, gonocytes and interstitial cells of the testis. {ECO:0000269|PubMed:10190901, ECO:0000269|PubMed:16049158}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IGF2BP2 full length protein - ab153107 from Abcam Category Protein Source Wheat germ Species Human

Human IGF2BP2 full length protein - ab153108 from Abcam Category Protein Source Wheat germ Species Human

Human IGF2BP2 full length protein - ab167738 from Abcam Category Protein Source HEK 293 cells Species Human

Human IGF2BP2 protein fragment - ab153109 from Abcam Category Protein Source Wheat germ Species Human

Human IGF2BP2 protein fragment - ab173053 from Abcam Category Protein Source E. coli Species Human

IGF2BP2 Antibody Blocking Peptide - LS-E59 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IGF2BP2 Antibody Blocking Peptide - LS-E14888 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IGF2BP2 Antibody Blocking Peptide - LS-E26585 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human IMP2/IGF2BP2 Protein - H00010644-P02 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human IMP2/IGF2BP2 Protein - H00010644-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human IMP2/IGF2BP2 Protein - H00010644-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Mouse-Igf2bp2-Antibody-N-term-Blocking-Peptide - BP19645a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg Species Mouse

IGF2BP2-Antibody-C-term-Blocking-peptide - BP10127b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

IGF2BP2 blocking peptide - GTX88840-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog

Human IGF2BP2,IMP2 protein - orb84028 from Biorbyt Category Protein Prices $417.00, $748.00 Sizes 20 μg, 50 μg Source Insect Species Human

Human IGF2BP2 protein - orb163441 from Biorbyt Category Protein Prices $408.00, $595.00, $2,074.00, $2,933.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

IGF2BP2 protein - orb197669 from Biorbyt Category Protein Prices $255.00, $391.00, $519.00 Sizes 10 μg, 50 μg, 100 μg Species Human

IGF2BP2 Blocking Peptide - 33R-7470 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human IGF2BP2 Protein - abx067235 from Abbexa Category Protein Source E.coli Species Human

IGF2BP2 Peptide - AC21-1421-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

IGF2BP2 - H00010644-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

IGF2BP2 - H00010644-P02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

IGF2BP2 - H00010644-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

IGF2BP2 - H00010644-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human IGF2BP2 - 230-00573-10 from RayBiotech Category Protein Prices $110.00 Sizes 10 µg Source Escherichia coli (E.coli) Species Human

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