Gene Symbol | MLLT3 |
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Entrez Gene | 4300 |
Alt Symbol | AF9, YEATS3 |
Species | Human |
Gene Type | protein-coding |
Description | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
Other Description | ALL1-fused gene from chromosome 9 protein|YEATS domain-containing protein 3|myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 3|myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein|protein AF-9 |
Swissprots | B7Z755 B2R7B3 D3DRJ8 P42568 Q8IVB0 B1AMQ2 |
Accessions | EAW58630 EAW58631 EAW58632 P42568 AK128222 AK225957 AK297587 BAH12621 AK301474 BAH13491 AK312914 BAG35760 AW451255 BC030550 BC036089 AAH36089 BI550359 BX649194 CAE46213 D16688 BAA04090 DC306929 DC345433 JF432808 ADZ16025 L13744 AAA58361 NM_001286691 NP_001273620 NM_004529 NP_004520 |
Function | Component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. {ECO:0000269|PubMed:20159561, ECO:0000269|PubMed:20471948}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00376}. |
Top Pathways | Transcriptional misregulation in cancer |
Human AF9 full length protein - ab152532 from Abcam
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Human AF9 peptide - ab32718 from Abcam
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MLLT3 / AF9 Antibody Blocking Peptide - LS-E8119 from LifeSpan Bioscience
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MLLT3 / AF9 Antibody Blocking Peptide - LS-E8120 from LifeSpan Bioscience
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MLLT3 / AF9 Antibody Blocking Peptide - LS-E8118 from LifeSpan Bioscience
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MLLT3 / AF9 Antibody Blocking Peptide - LS-E13835 from LifeSpan Bioscience
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MLLT3 / AF9 Antibody Blocking Peptide - LS-E13834 from LifeSpan Bioscience
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AF9 Blocking Peptide - NB100-1566PEP from Novus Biologicals
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Recombinant Human AF9 Protein - H00004300-P01 from Novus Biologicals
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MLLT3-Antibody-N-term-H54-Blocking-Peptide - BP6190c from Abgent, a WuXi AppTec company
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AF9-MLLT3-Antibody-Center-V422-Blocking-peptide - BP6190b from Abgent, a WuXi AppTec company
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AF9-MLLT3-Antibody-C-term-K486-Blocking-peptide - BP6190a from Abgent, a WuXi AppTec company
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MLLT3 Blocking Peptide - 33R-2694 from Fitzgerald
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MLLT3 Blocking Peptide - 33R-5761 from Fitzgerald
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MLLT3 / AF9 - H00004300-P01 from Acris Antibodies
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MLLT3 fusion protein - ag3528 from Proteintech Group
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Recombinant Human MLLT3, GST-tagged - MLLT3-908H from Creative Biomart
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Recombinant Human Protein AF-9(MLLT3) - CSB-YP014635HU CSB-EP014635HU CSB-BP014635HU CSB-MP014635HU from Cusabio
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MLLT3 Protein - abx164026 from Abbexa
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MLLT3 / AF9 - TP306283 from Acris Antibodies
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Protein AF-9 (MLLT3), Recombinant Protein - MBS968384 from MyBioSource
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AF9 Recombinant Protein Antigen - NBP1-90217PEP from Novus Biologicals
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AF9-MLLT3-Antibody-Center-H197-Blocking-peptide - BP6190d from Abgent, a WuXi AppTec company
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MLLT3 Peptide, Human - M34GP09571H from Creative Peptides
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Human MLLT3 protein - orb54751 from Biorbyt
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