NT5C

Gene Symbol NT5C
Entrez Gene 30833
Alt Symbol DNT, DNT1, HEL74, P5N2, PN-I, PN-II, UMPH2, cdN, dNT-1
Species Human
Gene Type protein-coding
Description 5', 3'-nucleotidase, cytosolic
Other Description 5' nucleotidase, deoxy (pyrimidine), cytosolic type C|5'(3')-deoxyribonucleotidase, cytosolic type|cytosolic 5',3'-pyrimidine nucleotidase|deoxy-5'-nucleotidase 1|epididymis luminal protein 74|uridine 5'-monophosphate phosphohydrolase 2|uridine 5-prime monophosphate hydrolase 2
Swissprots Q96HS6 Q8TCD5 Q9NP82
Accessions DAA00070 EAW89241 EAW89242 EAW89243 Q8TCD5 AF154829 AAF36534 AK000419 BAA91151 BC002516 BC008183 AAH08183 BC017454 AAH17454 BC022334 AAH22334 BC047763 BG034032 BQ431723 BU627693 EU794640 ACJ13694 HQ448006 ADQ32487 XM_006721850 XP_006721913 XM_011524700 XP_011523002 XR_429885 NM_001252377 NP_001239306 NM_014595 NP_055410 NR_045513
Function Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP.
Subcellular Location Cytoplasm.
Tissue Specificity Detected in skeletal muscle, heart and pancreas. {ECO:0000269|PubMed:10681516}.
Top Pathways Purine metabolism, Nicotinate and nicotinamide metabolism, Pyrimidine metabolism

dNT-1 CRISPR/Cas9 KO Plasmid (h) - sc-407070 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

dNT-1 HDR Plasmid (h) - sc-407070-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

dNT-1 Double Nickase Plasmid (h) - sc-407070-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

dNT-1 Double Nickase Plasmid (h2) - sc-407070-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

dNT-1 CRISPR Activation Plasmid (h) - sc-407070-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

dNT-1 CRISPR Activation Plasmid (h2) - sc-407070-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

dNT-1 Lentiviral Activation Particles (h) - sc-407070-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

dNT-1 Lentiviral Activation Particles (h2) - sc-407070-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

dNT-1 siRNA (h) - sc-38995 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

dNT-1 shRNA Plasmid (h) - sc-38995-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

dNT-1 shRNA (h) Lentiviral Particles - sc-38995-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NT5C RNAi - H00030833-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® Human Phosphatase - SIHP0354 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0352 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0353 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN15546 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15546 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01658 from Sigma-Aldrich

Category miRNA

NT5C siRNA (Human) - CRH9350 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NT5C (NM_014595.2) - SHH355508 from Creative biogene

Category siRNA
Species Reactivities Human

NT5C shRNA Plasmid (Human) - CHH9350 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NT5C miRNA 3'UTR clone - MiUTR3H-02379 from Creative biogene

Species Reactivities Human
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