Gene Symbol | NT5C |
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Entrez Gene | 30833 |
Alt Symbol | DNT, DNT1, HEL74, P5N2, PN-I, PN-II, UMPH2, cdN, dNT-1 |
Species | Human |
Gene Type | protein-coding |
Description | 5', 3'-nucleotidase, cytosolic |
Other Description | 5' nucleotidase, deoxy (pyrimidine), cytosolic type C|5'(3')-deoxyribonucleotidase, cytosolic type|cytosolic 5',3'-pyrimidine nucleotidase|deoxy-5'-nucleotidase 1|epididymis luminal protein 74|uridine 5'-monophosphate phosphohydrolase 2|uridine 5-prime monophosphate hydrolase 2 |
Swissprots | Q96HS6 Q8TCD5 Q9NP82 |
Accessions | DAA00070 EAW89241 EAW89242 EAW89243 Q8TCD5 AF154829 AAF36534 AK000419 BAA91151 BC002516 BC008183 AAH08183 BC017454 AAH17454 BC022334 AAH22334 BC047763 BG034032 BQ431723 BU627693 EU794640 ACJ13694 HQ448006 ADQ32487 XM_006721850 XP_006721913 XM_011524700 XP_011523002 XR_429885 NM_001252377 NP_001239306 NM_014595 NP_055410 NR_045513 |
Function | Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Detected in skeletal muscle, heart and pancreas. {ECO:0000269|PubMed:10681516}. |
Top Pathways | Purine metabolism, Nicotinate and nicotinamide metabolism, Pyrimidine metabolism |
Active Pasteurella multocida toxin full length protein - ab63832 from Abcam
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Human NT5C full length protein - ab162324 from Abcam
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Recombinant Human NT5C Protein - H00030833-P01 from Novus Biologicals
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NT5C - H00030833-P01-10 from Acris Antibodies
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NT5C - H00030833-P01-25 from Acris Antibodies
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NT5C fusion protein - Ag9862 from Proteintech Group
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NT5C fusion protein - ag9820 from Proteintech Group
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Recombinant Human NT5C, GST-tagged - NT5C-1380H from Creative Biomart
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Recombinant Human 5'(3')-deoxyribonucleotidase, cytosolic type(NT5C) - CSB-YP837431HU CSB-EP837431HU CSB-BP837431HU CSB-MP837431HU from Cusabio
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NT5C - TP304265 from Acris Antibodies
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5' (3')-deoxyribonucleotidase, cytosolic type (NT5C), Recombinant Protein - MBS1398510 from MyBioSource
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NT5C Recombinant Protein Antigen - NBP1-84564PEP from Novus Biologicals
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NT5C Recombinant Protein Antigen - NBP1-84563PEP from Novus Biologicals
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NT5C-Blocking-Peptide-N-Term - BP22072a from Abgent, a WuXi AppTec company
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NT5C-Blocking-Peptide-C-Term - BP22060b from Abgent, a WuXi AppTec company
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NT5C Peptide, Human - M34GP10658H from Creative Peptides
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NT5C Recombinant Protein (OPCD00213) - OPCD00213 from Aviva Systems Biology
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