Gene Symbol | PHB2 |
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Entrez Gene | 11331 |
Alt Symbol | BAP, BCAP37, Bap37, PNAS-141, REA, p22 |
Species | Human |
Gene Type | protein-coding |
Description | prohibitin 2 |
Other Description | B-cell associated protein|B-cell receptor-associated protein BAP37|D-prohibitin|prohibitin-2|repressor of estrogen receptor activity |
Swissprots | Q7KYU3 B4DP75 Q99623 Q92978 Q2YDA4 |
Accessions | AAB51324 EAW88699 Q99623 AF126021 AAF17231 AF150962 AAD38042 AF178980 AAF44345 AF279895 AAK07552 AK298217 BAG60487 AK301316 BAG62867 BC013228 BC014766 AAH14766 BC110322 AAI10323 DQ891808 ABM82734 EU176626 ABW03427 U72511 AAC51639 U72512 XR_242980 NM_001144831 NP_001138303 NM_001267700 NP_001254629 |
Function | Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging. {ECO:0000250|UniProtKB:O35129, ECO:0000269|PubMed:10359819, ECO:0000303|PubMed:11302691}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000250}. Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Also cytoplasmic and nuclear. {ECO:0000250}. |
Human REA full length protein - ab153180 from Abcam
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Human REA full length protein - ab153181 from Abcam
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Human REA full length protein - ab167836 from Abcam
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BAP / SIL1 Antibody Blocking Peptide - LS-E25591 from LifeSpan Bioscience
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BAP / SIL1 Antibody Blocking Peptide - LS-E16471 from LifeSpan Bioscience
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BAP / SIL1 Antibody Blocking Peptide - LS-E9610 from LifeSpan Bioscience
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Prohibitin 2 / PHB2 Antibody Blocking Peptide - LS-E22410 from LifeSpan Bioscience
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Prohibitin 2 / PHB2 Antibody Blocking Peptide - LS-E8819 from LifeSpan Bioscience
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Prohibitin 2 / PHB2 Antibody Blocking Peptide - LS-E8820 from LifeSpan Bioscience
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Prohibitin 2 / PHB2 Antibody Blocking Peptide - LS-E17482 from LifeSpan Bioscience
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Prohibitin 2 / PHB2 Antibody Blocking Peptide - LS-E17481 from LifeSpan Bioscience
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Prohibitin 2 Recombinant Protein - H00011331-P02 from Novus Biologicals
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Prohibitin 2 Recombinant Protein - H00011331-P01 from Novus Biologicals
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Recombinant Human Prohibitin 2 Protein - NBP2-23365 from Novus Biologicals
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Prohibitin 2 Peptide - P2449 from Novus Biologicals
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Prohibitin 2 Peptide - P2447 from Novus Biologicals
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PHB2-Antibody-Y128-Blocking-Peptide - BP7270d from Abgent, a WuXi AppTec company
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REA-PHB2-Antibody-N-term-Blocking-peptide - BP7270a from Abgent, a WuXi AppTec company
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PHB2 Protein Lysate (APL10992) - APL10992 from Aviva Systems Biology
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PHB2 Protein Lysate (APL10994) - APL10994 from Aviva Systems Biology
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PHB2 protein (His tag) - 80R-2889 from Fitzgerald
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Prohibitin 2 Blocking Peptide - 33R-9946 from Fitzgerald
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Prohibitin 2 Blocking Peptide - 33R-4533 from Fitzgerald
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SIL1 protein (His tag) - 80R-2320 from Fitzgerald
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Prohibitin-2 (1-299, His-tag) - AR51008PU-N from Acris Antibodies
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