PHB2

Gene Symbol PHB2
Entrez Gene 11331
Alt Symbol BAP, BCAP37, Bap37, PNAS-141, REA, p22
Species Human
Gene Type protein-coding
Description prohibitin 2
Other Description B-cell associated protein|B-cell receptor-associated protein BAP37|D-prohibitin|prohibitin-2|repressor of estrogen receptor activity
Swissprots Q7KYU3 B4DP75 Q99623 Q92978 Q2YDA4
Accessions AAB51324 EAW88699 Q99623 AF126021 AAF17231 AF150962 AAD38042 AF178980 AAF44345 AF279895 AAK07552 AK298217 BAG60487 AK301316 BAG62867 BC013228 BC014766 AAH14766 BC110322 AAI10323 DQ891808 ABM82734 EU176626 ABW03427 U72511 AAC51639 U72512 XR_242980 NM_001144831 NP_001138303 NM_001267700 NP_001254629
Function Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging. {ECO:0000250|UniProtKB:O35129, ECO:0000269|PubMed:10359819, ECO:0000303|PubMed:11302691}.
Subcellular Location Mitochondrion inner membrane {ECO:0000250}. Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Also cytoplasmic and nuclear. {ECO:0000250}.

Prohibitin 2 CRISPR/Cas9 KO Plasmid (h) - sc-401282 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Prohibitin 2 HDR Plasmid (h) - sc-401282-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Prohibitin 2 Double Nickase Plasmid (h) - sc-401282-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Prohibitin 2 Double Nickase Plasmid (h2) - sc-401282-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Prohibitin 2 CRISPR Activation Plasmid (h) - sc-401282-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Prohibitin 2 CRISPR Activation Plasmid (h2) - sc-401282-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Prohibitin 2 Lentiviral Activation Particles (h) - sc-401282-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Prohibitin 2 Lentiviral Activation Particles (h2) - sc-401282-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Prohibitin 2 siRNA (h) - sc-45849 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Prohibitin 2 shRNA Plasmid (h) - sc-45849-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Prohibitin 2 shRNA (h) Lentiviral Particles - sc-45849-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Prohibitin 2 RNAi - H00011331-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU104281 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16710 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16710 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PHB2 siRNA (Human) - CRH7758 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Prohibitin 2 CRISPR/Cas9 KO Plasmid (h2) - sc-401282-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Prohibitin 2 HDR Plasmid (h2) - sc-401282-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHB2 shRNA Plasmid (Human) - CHH7758 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PHB2 miRNA 3'UTR clone - MiUTR3H-11423 from Creative biogene

Species Reactivities Human
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