PHB2

Gene Symbol PHB2
Entrez Gene 11331
Alt Symbol BAP, BCAP37, Bap37, PNAS-141, REA, p22
Species Human
Gene Type protein-coding
Description prohibitin 2
Other Description B-cell associated protein|B-cell receptor-associated protein BAP37|D-prohibitin|prohibitin-2|repressor of estrogen receptor activity
Swissprots Q7KYU3 B4DP75 Q99623 Q92978 Q2YDA4
Accessions AAB51324 EAW88699 Q99623 AF126021 AAF17231 AF150962 AAD38042 AF178980 AAF44345 AF279895 AAK07552 AK298217 BAG60487 AK301316 BAG62867 BC013228 BC014766 AAH14766 BC110322 AAI10323 DQ891808 ABM82734 EU176626 ABW03427 U72511 AAC51639 U72512 XR_242980 NM_001144831 NP_001138303 NM_001267700 NP_001254629
Function Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging. {ECO:0000250|UniProtKB:O35129, ECO:0000269|PubMed:10359819, ECO:0000303|PubMed:11302691}.
Subcellular Location Mitochondrion inner membrane {ECO:0000250}. Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Also cytoplasmic and nuclear. {ECO:0000250}.

PHB2 (E1Z5A) Rabbit mAb - 14085 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone E1Z5A
Western blot analysis of extracts from various cell lines using PHB2 (E1Z5A) Rabbit mAb.

PHB2 Antibody - 12101 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

Prohibitin 2 (A-2) - sc-133094 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Prohibitin 2 (A-2): sc-133094. Western blot analysis of Prohibitin 2 expression in non-transfected 293T: sc-117752 (A), human Prohibitin 2 transfected 293T: sc-111933 (B) and BJAB (C) whole cell lysates.

Prohibitin 2 (C-13) - sc-46461 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Prohibitin 2 (C-13): sc-46461. Immunoperoxidase staining of formalin fixed, paraffin-embedded human tonsil tissue showing nuclear staining of cells in germinal centers and non-germinal centers.

Prohibitin 2 (H-80) - sc-67045 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Prohibitin 2 (H-80): sc-67045. Western blot analysis of Prohibitin 2 expression in MCF7 (A), SK-BR-3 (B) and NIH/3T3 (C) whole cell lysates and human recombinant Prohibitin 2 fusion protein (D).

Prohibitin 2 (N-13) - sc-46464 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Prohibitin 2 (N-13): sc-46464. Immunoperoxidase staining of formalin fixed, paraffin-embedded human spleen tissue showing cytoplasmic staining of cells in white pulp and cells in red pulp.

Prohibitin 2 (T-22) - sc-130854 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
Prohibitin 2 (T-22): sc-130854. Western blot analysis of Prohibitin 2 expression in BJAB whole cell lysate.

p-Prohibitin 2 (Tyr 128) - sc-130604 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-REA antibody - ab15019 from Abcam

Prices $401.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-REA antibody (ab15019) at 1 µg/ml + Human brain whole tissue lysate at 50 µgSecondaryHRP-conjugated goat anti-rabbit IgG (H+L) polyclonal at 3000 mg/mldeveloped using the ECL techniquePerformed under reducing conditions.

Anti-REA antibody - ab135642 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-REA antibody (ab135642) at 1/50 dilution + 293 cell lysate at 35 µg

Anti-REA antibody - ab82547 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab82547, at a 1:250 dilution, staining Human REA in breast adenocarcinoma, using Immunohistochemistry, Formalin/PFA-fixed paraffin-embedded tissue.

Anti-REA antibody [EPR14522] - ab181838 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14522
Anti-REA antibody [EPR14522] (ab181838) at 1/10000 dilution + HeLa cell lysate at 20 µgSecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-REA antibody [EPR14523] - ab182139 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14523
All lanes : Anti-REA antibody [EPR14523] (ab182139) at 1/20000 dilutionLane 1 : HT-1080 cell lysateLane 2 : HeLa cell lysateLane 3 : 293T cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-Prohibitin 2 / PHB2 Antibody (aa1-50) - LS-C287526 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human REA by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-REA used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

Anti-Prohibitin 2 / PHB2 Antibody (aa1-50) - LS-C286327 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human REA by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-REA used at a dilution of 1:250. Detection: DAB.

Anti-Prohibitin 2 / PHB2 Antibody (C-Terminus) IHC-plus™ - LS-B1889 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-PHB2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1889 dilution 1:50.

Anti-Prohibitin 2 / PHB2 Antibody (aa111-128) - LS-C313085 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Prohibitin 2 / PHB2 antibody. IHC(P): Human Lung Cancer Tissue.

Anti-Prohibitin 2 / PHB2 Antibody (Tyr248) - LS-C100839 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PHB2 Antibody (Y248)immunohistochemistry of formalin-fixed and paraffin-embedded human prostate carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-Prohibitin 2 / PHB2 Antibody (Tyr128) IHC-plus™ - LS-B4780 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human, Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-Prohibitin 2 / PHB2 Antibody (aa45-299) - LS-C185463 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Prohibitin 2 antibody detects PHB2 protein at cytosol on U87 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded U87 xenograft. Prohibitin 2 antibody dilution:1:500.

Anti-Prohibitin 2 / PHB2 Antibody (aa89-299) - LS-C75080 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-Prohibitin 2 / PHB2 Antibody (aa1-50) - LS-C90864 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Prohibitin 2 / PHB2 Antibody (C-Terminus) - LS-C90866 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-Prohibitin 2 / PHB2 Antibody (C-Terminus) - LS-C90868 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Prohibitin 2 / PHB2 Antibody (aa74-123) - LS-C81214 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.
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