JOSD1

Gene Symbol JOSD1
Entrez Gene 9929
Alt Symbol dJ508I15.2
Species Human
Gene Type protein-coding
Description Josephin domain containing 1
Other Description Josephin-1|josephin domain-containing 1|josephin domain-containing protein 1
Swissprots A8K712 Q15040
Accessions EAW60259 EAW60260 Q15040 AK291827 BAF84516 BC015026 AAH15026 BX538323 CR456473 CAG30359 CR456923 CAG33204 CU013023 CAK54454 CU013311 CAK54753 D31884 BAA06682 XM_005261876 XP_005261933 XM_005261877 XP_005261934 XM_005261878 XP_005261935 XM_005261879 XP_005261936 NM_014876 NP_055691
Function Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cell motility independently of its catalytic activity. {ECO:0000269|PubMed:21118805, ECO:0000269|PubMed:23625928}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:23625928}. Cytoplasm {ECO:0000269|PubMed:23625928}. Note=Ubiquitination increases localization the plasma membrane. In the cytosol, the unubiquitinated form may be associated with the cytoskeleton via ACTB-binding.

Josephin-1 CRISPR/Cas9 KO Plasmid (h) - sc-411391 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Josephin-1 HDR Plasmid (h) - sc-411391-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Josephin-1 Double Nickase Plasmid (h) - sc-411391-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Josephin-1 Double Nickase Plasmid (h2) - sc-411391-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Josephin-1 CRISPR Activation Plasmid (h) - sc-411391-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Josephin-1 CRISPR Activation Plasmid (h2) - sc-411391-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Josephin-1 Lentiviral Activation Particles (h) - sc-411391-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Josephin-1 Lentiviral Activation Particles (h2) - sc-411391-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Josephin-1 siRNA (h) - sc-75361 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Josephin-1 shRNA Plasmid (h) - sc-75361-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Josephin-1 shRNA (h) Lentiviral Particles - sc-75361-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU039561 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10874 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10874 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11121 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11121

JOSD1 siRNA (Human) - CRH6674 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

JOSD1, siRNA - MBS8206259 from MyBioSource

Category siRNA
Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human JOSD1 (NM_014876.5) - SHH322143 from Creative biogene

Category siRNA
Species Reactivities Human

JOSD1 shRNA Plasmid (Human) - CHH6674 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

JOSD1 miRNA 3'UTR clone - MiUTR4H-TG04634 from Creative biogene

Species Reactivities Human
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