Gene Symbol | JOSD1 |
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Entrez Gene | 9929 |
Alt Symbol | dJ508I15.2 |
Species | Human |
Gene Type | protein-coding |
Description | Josephin domain containing 1 |
Other Description | Josephin-1|josephin domain-containing 1|josephin domain-containing protein 1 |
Swissprots | A8K712 Q15040 |
Accessions | EAW60259 EAW60260 Q15040 AK291827 BAF84516 BC015026 AAH15026 BX538323 CR456473 CAG30359 CR456923 CAG33204 CU013023 CAK54454 CU013311 CAK54753 D31884 BAA06682 XM_005261876 XP_005261933 XM_005261877 XP_005261934 XM_005261878 XP_005261935 XM_005261879 XP_005261936 NM_014876 NP_055691 |
Function | Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cell motility independently of its catalytic activity. {ECO:0000269|PubMed:21118805, ECO:0000269|PubMed:23625928}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:23625928}. Cytoplasm {ECO:0000269|PubMed:23625928}. Note=Ubiquitination increases localization the plasma membrane. In the cytosol, the unubiquitinated form may be associated with the cytoskeleton via ACTB-binding. |
Josephin-1 (K-13) - sc-86154 from Santa Cruz Biotechnology
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Josephin-1 (N-17) - sc-86155 from Santa Cruz Biotechnology
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Anti-JOSD1 antibody [3B11] - ab118273 from Abcam
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Anti-Josephin-1 antibody - ab118221 from Abcam
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Anti-JOSD1 Antibody (aa44-188) - LS-C178648 from LifeSpan Bioscience
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Anti-JOSD1 Antibody (clone 3B11) - LS-C337205 from LifeSpan Bioscience
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Anti-JOSD1 Antibody (N-Terminus) - LS-C187057 from LifeSpan Bioscience
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Anti-JOSD1 Antibody (N-Terminus) - LS-C187058 from LifeSpan Bioscience
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Josephin1 Antibody - NBP1-87864 from Novus Biologicals
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Josephin1 Antibody (3B11) - NBP2-03442 from Novus Biologicals
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Anti-JOSD1 antibody produced in rabbit - HPA001168 from Sigma-Aldrich
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JOSD1 Antibody - N-terminal region (ARP70608_P050) - ARP70608_P050 from Aviva Systems Biology
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JOSD1 Antibody - N-terminal region (ARP70609_P050) - ARP70609_P050 from Aviva Systems Biology
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JOSD1 antibody - orb78078 from Biorbyt
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JOSD1 Antibody - abx036467 from Abbexa
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JOSD1, Polyclonal Antibody - MBS416851 from MyBioSource
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JOSD1, Polyclonal Antibody - MBS852847 from MyBioSource
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JOSD1 Antibody - 39621 from Signalway Antibody
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JOSD1 Antibody - E305576 from Enogene
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Anti-JOSD1 (aa 44-188) polyclonal antibody - DPABH-07419 from Creative Diagnostics
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Rabbit anti-Human JOSD1 polyclonal antibody - DPABH-12734 from Creative Diagnostics
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Anti-JOSD1 monoclonal antibody, clone 4C22 - DCABH-748 from Creative Diagnostics
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Josephin-1 / JOSD1 antibody - TA502210 from Acris Antibodies
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Josephin-1 (H-51) - sc-368909 from Santa Cruz Biotechnology
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Josephin-1 / JOSD1 antibody - TA337366 from Acris Antibodies
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