PTPN5

Gene Symbol	PTPN5
Entrez Gene	84867
Alt Symbol	PTPSTEP, STEP
Species	Human
Gene Type	protein-coding
Description	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
Other Description	neural-specific protein-tyrosine phosphatase|protein-tyrosine phosphatase striatum-enriched|striatum-enriched protein-tyrosine phosphatase|tyrosine-protein phosphatase non-receptor type 5
Swissprots	B7Z386 B3KXG7 Q8NDP8 Q8N2A1 D3DQY7 B7ZAF5 Q6P1Z2 P54829
Accessions	AAA87555 CCQ43780 EAW68363 EAW68364 EAW68365 EAW68366 EAW68367 EAW68368 P54829 AK027333 AK055450 AK090923 BAC03548 AK127312 BAG54479 AK294374 BAH11749 AK294673 BAH11844 AK295604 BAH12122 AK316270 BAH14641 AL832541 CAD38632 BC039897 AAH39897 BC046435 AAH46435 BC064807 AAH64807 XM_011520411 XP_011518713 XM_011520412 XP_011518714 NM_001039970 NP_001035059 NM_001278236 NP_001265165 NM_001278238 NP_001265167 NM_001278239 NP_001265168 NM_006906 NP_008837 NM_032781 NP_116170
Function	May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors. {ECO:0000269|PubMed:21777200}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Top Pathways	MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Non-phospho-STEP (Ser221) (D74H3) XP ® Rabbit mAb - 5659 from Cell Signaling Technology Prices $318.00 Sizes 100 µl (10 western blots) Host Rabbit Clonality Monoclonal Clone D74H3

STEP (D7E2) Rabbit mAb - 9017 from Cell Signaling Technology Prices $246.00 Sizes 100 µl (10 western blots) Host Rabbit Clonality Monoclonal Clone D7E2

STEP (23E5) Mouse mAb - 4396 from Cell Signaling Technology Prices $246.00 Sizes 100 µl (10 western blots) Host Mouse Clonality Monoclonal Clone 23E5

STEP (D9H3) Rabbit mAb - 9069 from Cell Signaling Technology Prices $246.00 Sizes 100 µl (10 western blots) Host Rabbit Clonality Monoclonal Clone D9H3

STEP Antibody - 4817 from Cell Signaling Technology Prices $246.00 Sizes 100 µl (10 western blots) Host Rabbit Clonality Polyclonal

STEP (C-12) - sc-22986 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

STEP (H-44) - sc-367345 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-STEP / PTPN5 antibody - ab129812 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-STEP / PTPN5 antibody [T41] - ab77123 from Abcam Prices $370.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone T41

Anti-PTPN5 / STEP Antibody (aa57-74) - LS-C124455 from LifeSpan Bioscience Prices $435.00 Sizes 100 µl Host Mouse Clonality Monoclonal

Anti-PTPN5 / STEP Antibody (N-Terminus) - LS-C131722 from LifeSpan Bioscience Prices $445.00 Sizes 100 µl Host Mouse Clonality Monoclonal

Anti-PTPN5 / STEP Antibody (aa1-30, AP) - LS-C239603 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PTPN5 / STEP Antibody (aa1-30, APC) - LS-C239604 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PTPN5 / STEP Antibody (aa1-30, Biotin) - LS-C239605 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PTPN5 / STEP Antibody (aa1-30, FITC) - LS-C239606 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PTPN5 / STEP Antibody (aa1-30, PE) - LS-C239607 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PTPN5 / STEP Antibody (N-Terminus, AP) - LS-C245478 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PTPN5 / STEP Antibody (N-Terminus, APC) - LS-C245480 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PTPN5 / STEP Antibody (N-Terminus, Biotin) - LS-C245479 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PTPN5 / STEP Antibody (N-Terminus, PE) - LS-C245482 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PTPN5 / STEP Antibody (N-Terminus, FITC) - LS-C245481 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PTPN5 / STEP Antibody (aa1-30, Azide-free, HRP) - LS-C248586 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PTPN5 / STEP Antibody (aa1-30) - LS-C324420 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PTPN5 / STEP Antibody (N-Terminus, Azide-free, HRP) - LS-C247792 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PTPN5 / STEP Antibody (aa57-74) - LS-C152764 from LifeSpan Bioscience Prices $445.00 Sizes 100 µg Host Mouse Clonality Monoclonal

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