PTPN5

Gene Symbol	PTPN5
Entrez Gene	84867
Alt Symbol	PTPSTEP, STEP
Species	Human
Gene Type	protein-coding
Description	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
Other Description	neural-specific protein-tyrosine phosphatase|protein-tyrosine phosphatase striatum-enriched|striatum-enriched protein-tyrosine phosphatase|tyrosine-protein phosphatase non-receptor type 5
Swissprots	B7Z386 B3KXG7 Q8NDP8 Q8N2A1 D3DQY7 B7ZAF5 Q6P1Z2 P54829
Accessions	AAA87555 CCQ43780 EAW68363 EAW68364 EAW68365 EAW68366 EAW68367 EAW68368 P54829 AK027333 AK055450 AK090923 BAC03548 AK127312 BAG54479 AK294374 BAH11749 AK294673 BAH11844 AK295604 BAH12122 AK316270 BAH14641 AL832541 CAD38632 BC039897 AAH39897 BC046435 AAH46435 BC064807 AAH64807 XM_011520411 XP_011518713 XM_011520412 XP_011518714 NM_001039970 NP_001035059 NM_001278236 NP_001265165 NM_001278238 NP_001265167 NM_001278239 NP_001265168 NM_006906 NP_008837 NM_032781 NP_116170
Function	May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors. {ECO:0000269|PubMed:21777200}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Top Pathways	MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

STEP CRISPR/Cas9 KO Plasmid (h) - sc-407340 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

STEP HDR Plasmid (h) - sc-407340-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

STEP Double Nickase Plasmid (h) - sc-407340-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

STEP Double Nickase Plasmid (h2) - sc-407340-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

STEP CRISPR Activation Plasmid (h) - sc-407340-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

STEP CRISPR Activation Plasmid (h2) - sc-407340-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

STEP Lentiviral Activation Particles (h) - sc-407340-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

STEP Lentiviral Activation Particles (h2) - sc-407340-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

STEP siRNA (h) - sc-44128 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

STEP shRNA Plasmid (h) - sc-44128-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

STEP shRNA (h) Lentiviral Particles - sc-44128-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

STEP RNAi - H00084867-R01 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU091581 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® Human Phosphatase - SIHP0768 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0766 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0767 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN17702 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17702 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07538 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr07538

PTPN5 siRNA (Human) - CRJ3650 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human PTPN5 (NM_032781.3) - SHH386588 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human PTPN5(NM_006906.1) - SHR152652 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human PTPN5(NM_001039970.1) - SHR152754 from Creative biogene Category siRNA Species Reactivities Human

PTPN5 shRNA Plasmid (Human) - CHJ3650 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

PTPN5 miRNA 3'UTR clone - MiUTR1H-08467 from Creative biogene Species Reactivities Human

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