Gene Symbol | PTPN5 |
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Entrez Gene | 84867 |
Alt Symbol | PTPSTEP, STEP |
Species | Human |
Gene Type | protein-coding |
Description | protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) |
Other Description | neural-specific protein-tyrosine phosphatase|protein-tyrosine phosphatase striatum-enriched|striatum-enriched protein-tyrosine phosphatase|tyrosine-protein phosphatase non-receptor type 5 |
Swissprots | B7Z386 B3KXG7 Q8NDP8 Q8N2A1 D3DQY7 B7ZAF5 Q6P1Z2 P54829 |
Accessions | AAA87555 CCQ43780 EAW68363 EAW68364 EAW68365 EAW68366 EAW68367 EAW68368 P54829 AK027333 AK055450 AK090923 BAC03548 AK127312 BAG54479 AK294374 BAH11749 AK294673 BAH11844 AK295604 BAH12122 AK316270 BAH14641 AL832541 CAD38632 BC039897 AAH39897 BC046435 AAH46435 BC064807 AAH64807 XM_011520411 XP_011518713 XM_011520412 XP_011518714 NM_001039970 NP_001035059 NM_001278236 NP_001265165 NM_001278238 NP_001265167 NM_001278239 NP_001265168 NM_006906 NP_008837 NM_032781 NP_116170 |
Function | May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors. {ECO:0000269|PubMed:21777200}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | MAPK signaling pathway |
Human STEP / PTPN5 full length protein - ab132095 from Abcam
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Human STEP / PTPN5 peptide - ab22661 from Abcam
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PTPN5 / STEP Antibody Blocking Peptide - LS-E4672 from LifeSpan Bioscience
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PTPN5 / STEP Antibody Blocking Peptide - LS-E9574 from LifeSpan Bioscience
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Recombinant Human STEP Protein - H00084867-P01 from Novus Biologicals
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Recombinant Human STEP Protein - H00084867-Q01 from Novus Biologicals
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STEP Peptide - P3263 from Novus Biologicals
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PTPN5-Antibody-N-term-Blocking-Peptide - BP17036a from Abgent, a WuXi AppTec company
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STEP--PTPN5-Antibody-N-Term-Blocking-peptide - BP8430a from Abgent, a WuXi AppTec company
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Human PTPN5 protein - orb244474 from Biorbyt
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PTPN5 Blocking Peptide - 33R-9722 from Fitzgerald
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PTPN5 / STEP - H00084867-P01-10 from Acris Antibodies
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PTPN5 / STEP - H00084867-P01-25 from Acris Antibodies
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PTPN5 / STEP - H00084867-Q01-10 from Acris Antibodies
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PTPN5 / STEP - H00084867-Q01-25 from Acris Antibodies
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PTPN5 Peptide - 8013P from ProSci
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PTPN5 fusion protein - Ag5974 from Proteintech Group
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Recombinant Human PTPN5, GST-tagged - PTPN5-2057H from Creative Biomart
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Recombinant human Tyrosine-protein phosphatase non-receptor type 5 - CSB-EP019042HU CSB-BP019042HU CSB-MP019042HU from Cusabio
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Recombinant human Tyrosine-protein phosphatase non-receptor type 5 - CSB-EP019042HU from Cusabio
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Recombinant Human Tyrosine-protein phosphatase non-receptor type 5(PTPN5) - CSB-YP019042HU CSB-BP019042HU CSB-MP019042HU from Cusabio
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PTPN5 / STEP (transcript variant 1) - TP308953 from Acris Antibodies
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PTPN5 / STEP (transcript variant 2) - TP317371 from Acris Antibodies
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Recombinant Protein Tyrosine Phosphatase, Non Receptor Type 5 (PTPN5) - RPD588Hu01 from Uscn Life Science Inc.
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Recombinant Protein Tyrosine Phosphatase, Non Receptor Type 5 (PTPN5) - RPD588Mu01 from Uscn Life Science Inc.
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