| Gene Symbol |
PTPN5
|
| Entrez Gene |
84867
|
| Alt Symbol |
PTPSTEP, STEP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
|
| Other Description |
neural-specific protein-tyrosine phosphatase|protein-tyrosine phosphatase striatum-enriched|striatum-enriched protein-tyrosine phosphatase|tyrosine-protein phosphatase non-receptor type 5
|
| Swissprots |
B7Z386 B3KXG7 Q8NDP8 Q8N2A1 D3DQY7 B7ZAF5 Q6P1Z2 P54829
|
| Accessions |
AAA87555 CCQ43780 EAW68363 EAW68364 EAW68365 EAW68366 EAW68367 EAW68368 P54829 AK027333 AK055450 AK090923 BAC03548 AK127312 BAG54479 AK294374 BAH11749 AK294673 BAH11844 AK295604 BAH12122 AK316270 BAH14641 AL832541 CAD38632 BC039897 AAH39897 BC046435 AAH46435 BC064807 AAH64807 XM_011520411 XP_011518713 XM_011520412 XP_011518714 NM_001039970 NP_001035059 NM_001278236 NP_001265165 NM_001278238 NP_001265167 NM_001278239 NP_001265168 NM_006906 NP_008837 NM_032781 NP_116170
|
| Function |
May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors. {ECO:0000269|PubMed:21777200}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Top Pathways |
MAPK signaling pathway
|