TWF1

Gene Symbol	TWF1
Entrez Gene	5756
Alt Symbol	A6, PTK9
Species	Human
Gene Type	protein-coding
Description	twinfilin actin-binding protein 1
Other Description	A6 protein tyrosine kinase|PTK9 protein tyrosine kinase 9|protein A6|protein tyrosine kinase 9|twinfilin, actin-binding protein, homolog 1|twinfilin-1
Swissprots	Q86XL6 B3KXS6 Q8TCD3 Q59G07 Q6FHL6 Q6FHJ1 Q6NUK9 B4DLX9 Q12792 A8K5A8 Q5U0B1
Accessions	EAW57868 EAW57869 EAW57870 Q12792 AB209302 BAD92539 AK127868 BAG54588 AK291223 BAF83912 AK297206 BAG59691 BC022344 AAH22344 BC022491 BC043148 AAH43148 BC068548 AAH68548 BT019691 AAV38497 CR541736 CAG46536 CR541761 CAG46561 EU832120 ACE87470 EU832214 ACE86784 U02680 AAC50062 NM_001242397 NP_001229326 NM_002822 NP_002813 NR_073472 NR_073473 NM_198974
Function	Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Diffuse cytoplasmic localization with perinuclear and G-actin-rich cortical actin structures sublocalization. Also found at membrane ruffles and cell-cell contacts (By similarity). {ECO:0000250}.
Tissue Specificity	Expressed at high levels in the colon, testis, ovary, prostate and lung. Expressed at lower levels in the brain, bladder and heart. Not detected in liver. {ECO:0000269|PubMed:7507208}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Twinfilin-1 CRISPR/Cas9 KO Plasmid (h) - sc-417201 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Twinfilin-1 HDR Plasmid (h) - sc-417201-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Twinfilin-1 Double Nickase Plasmid (h) - sc-417201-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Twinfilin-1 Double Nickase Plasmid (h2) - sc-417201-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Twinfilin-1 CRISPR Activation Plasmid (h) - sc-417201-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Twinfilin-1 CRISPR Activation Plasmid (h2) - sc-417201-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Twinfilin-1 Lentiviral Activation Particles (h) - sc-417201-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Twinfilin-1 Lentiviral Activation Particles (h2) - sc-417201-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Twinfilin-1 siRNA (h) - sc-61738 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Twinfilin-1 shRNA Plasmid (h) - sc-61738-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Twinfilin-1 shRNA (h) Lentiviral Particles - sc-61738-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PTK9 RNAi - H00005756-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

PTK9 RNAi - H00005756-R03 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

PTK9 RNAi - H00005756-R04 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU062351 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® siRNA - SIHK2385 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK2387 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK2386 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN22291 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22291 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR13180 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr13180

TWF1 siRNA (Human) - CRH3892 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TWF1 - MBS8202828 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

Human TWF1 siRNA - orb264394 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TWF1 shRNA Plasmid (Human) - CHH3892 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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