AWAT1

Gene Symbol AWAT1
Entrez Gene 158833
Alt Symbol DGA2, DGAT2L3
Species Human
Gene Type protein-coding
Description acyl-CoA wax alcohol acyltransferase 1
Other Description diacyl-glycerol acyltransferase 2|diacylglycerol O-acyltransferase 2-like 3|diacylglycerol O-acyltransferase 2-like protein 3|diacylglycerol acyltransferase 2|long-chain-alcohol O-fatty-acyltransferase 1
Swissprots Q58HT5 Q5JT21 Q6IEE4
Accessions EAX05353 Q58HT5 AY947638 AAX48018 BC039181 BC146428 AAI46429 BC153034 AAI53035 BN000155 CAD89266 W68831 NM_001013579 NP_001013597
Function Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has a preference for arachidyl alcohol as well as decyl alcohol, demonstrating its relatively poor activity using saturated long chain alcohols (C16, C18, and C20). {ECO:0000269|PubMed:15671038}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity Predominantly expressed in skin, where it is limited to the sebaceous gland. Expressed in more mature, centrally located cells just before their rupture and sebum release. Also expressed in all tissues except spleen. Expressed at higher level in thymus, prostate and testis. {ECO:0000269|PubMed:15671038}.

AWAT1 CRISPR/Cas9 KO Plasmid (h) - sc-414804 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AWAT1 HDR Plasmid (h) - sc-414804-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AWAT1 Double Nickase Plasmid (h) - sc-414804-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AWAT1 Double Nickase Plasmid (h2) - sc-414804-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AWAT1 CRISPR Activation Plasmid (h) - sc-414804-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AWAT1 CRISPR Activation Plasmid (h2) - sc-414804-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AWAT1 Lentiviral Activation Particles (h) - sc-414804-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AWAT1 Lentiviral Activation Particles (h2) - sc-414804-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AWAT1 siRNA (h) - sc-91059 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AWAT1 shRNA Plasmid (h) - sc-91059-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AWAT1 shRNA (h) Lentiviral Particles - sc-91059-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU146601 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3783 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3783 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

AWAT1 siRNA (Human) - CRJ5878 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AWAT1 - MBS8218168 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AWAT1 (NM_001013579.2) - SHH243910 from Creative biogene

Category siRNA
Species Reactivities Human

Human AWAT1 siRNA - orb276379 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AWAT1 shRNA Plasmid (Human) - CHJ5878 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AWAT1 miRNA 3'UTR clone - MiUTR4H-TG10660 from Creative biogene

Species Reactivities Human
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