Gene Symbol | THPO |
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Entrez Gene | 7066 |
Alt Symbol | MGDF, MKCSF, ML, MPLLG, THCYT1, TPO |
Species | Human |
Gene Type | protein-coding |
Description | thrombopoietin |
Other Description | MPL ligand|c-mpl ligand|megakaryocyte colony-stimulating factor|megakaryocyte growth and development factor|megakaryocyte stimulating factor|myeloproliferative leukemia virus oncogene ligand|prepro-thrombopoietin |
Swissprots | P40225 B7ZLR8 A1L3Y0 Q15791 Q15792 Q15790 B9EGA8 Q13020 |
Accessions | AAA74083 AAB33390 AAC37568 BAA06807 EAW78243 EAW78244 EAW78245 P40225 AA479058 AA480029 AB014681 BAA34930 AB014682 BAA34931 AB014683 BAA34932 AB102890 BAD89419 AB102892 BAD89421 AB102894 BAD89423 AK311002 BC130322 AAI30323 BC136338 AAI36339 BC143982 AAI43983 BX108191 D32047 BAA21930 L33410 AAA59857 L36052 AAC37566 U11025 AAA50553 U42977 U59493 AAB03392 U59494 AAB03393 U59495 AAB03394 XM_011513113 XP_011511415 NM_000460 NP_000451 NM_001177597 NP_001171068 NM_001177598 NP_001171069 NM_001289997 NP_001276926 NM_001289998 NP_001276927 NM_001290003 NP_001276932 NM_001290022 NP_001276951 NM_001290026 NP_001276955 NM_001290027 NP_001276956 NM_001290028 NP_001276957 NM_199228 NM_199356 |
Function | Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. |
Subcellular Location | Secreted. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage |
Active human Thrombopoietin protein fragment - ab9719 from Abcam
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Active human Thrombopoietin protein fragment - ab179492 from Abcam
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Active mouse Thrombopoietin full length protein - ab170079 from Abcam
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Active mouse Thrombopoietin full length protein - ab191654 from Abcam
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Active mouse Thrombopoietin protein fragment - ab73295 from Abcam
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Human Thrombopoietin full length protein - ab99003 from Abcam
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Human Thrombopoietin peptide - ab105988 from Abcam
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Human Thrombopoietin peptide - ab93626 from Abcam
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THPO / TPO / Thrombopoietin Antibody Blocking Peptide - LS-E21491 from LifeSpan Bioscience
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THPO / TPO / Thrombopoietin Antibody Blocking Peptide - LS-E21492 from LifeSpan Bioscience
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THPO / TPO / Thrombopoietin Antibody Blocking Peptide - LS-E9052 from LifeSpan Bioscience
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THPO / TPO / Thrombopoietin Antibody Blocking Peptide - LS-E9053 from LifeSpan Bioscience
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Thrombopoietin/Tpo Recombinant Protein - H00007066-P01 from Novus Biologicals
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Thrombopoietin/Tpo Recombinant Protein - P3680 from Novus Biologicals
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Thrombopoietin/Tpo Recombinant Protein - P4373 from Novus Biologicals
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Thrombopoietin/Tpo Peptide - P2568 from Novus Biologicals
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Thrombopoietin-TPO-Antibody-Center-Blocking-Peptide - BP7557c from Abgent, a WuXi AppTec company
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Thrombopoietin-TPO-Antibody-C-term-Blocking-peptide - BP7557b from Abgent, a WuXi AppTec company
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Thrombopoietin Recombinant Protein (Active) - GTX48125-PRO from GeneTex
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Recombinant Human Thrombopoietin - 288-TP-005 from R&D Systems
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Recombinant Human Thrombopoietin - 288-TP-01M from R&D Systems
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Recombinant Human Thrombopoietin - 288-TP-025 from R&D Systems
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Recombinant Human Thrombopoietin - 288-TP-200 from R&D Systems
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Recombinant Human Thrombopoietin, CF - 288-TP-005/CF from R&D Systems
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Recombinant Human Thrombopoietin, CF - 288-TP-01M/CF from R&D Systems
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