THPO

Gene Symbol THPO
Entrez Gene 7066
Alt Symbol MGDF, MKCSF, ML, MPLLG, THCYT1, TPO
Species Human
Gene Type protein-coding
Description thrombopoietin
Other Description MPL ligand|c-mpl ligand|megakaryocyte colony-stimulating factor|megakaryocyte growth and development factor|megakaryocyte stimulating factor|myeloproliferative leukemia virus oncogene ligand|prepro-thrombopoietin
Swissprots P40225 B7ZLR8 A1L3Y0 Q15791 Q15792 Q15790 B9EGA8 Q13020
Accessions AAA74083 AAB33390 AAC37568 BAA06807 EAW78243 EAW78244 EAW78245 P40225 AA479058 AA480029 AB014681 BAA34930 AB014682 BAA34931 AB014683 BAA34932 AB102890 BAD89419 AB102892 BAD89421 AB102894 BAD89423 AK311002 BC130322 AAI30323 BC136338 AAI36339 BC143982 AAI43983 BX108191 D32047 BAA21930 L33410 AAA59857 L36052 AAC37566 U11025 AAA50553 U42977 U59493 AAB03392 U59494 AAB03393 U59495 AAB03394 XM_011513113 XP_011511415 NM_000460 NP_000451 NM_001177597 NP_001171068 NM_001177598 NP_001171069 NM_001289997 NP_001276926 NM_001289998 NP_001276927 NM_001290003 NP_001276932 NM_001290022 NP_001276951 NM_001290026 NP_001276955 NM_001290027 NP_001276956 NM_001290028 NP_001276957 NM_199228 NM_199356
Function Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
Subcellular Location Secreted.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage

TPO (F-3) - sc-374045 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TPO (F-3): sc-374045. Western blot analysis of mouse recombinant TPO.

TPO (H-68) - sc-366265 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

TPO (M-20) - sc-1299 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TPO (M-20): sc-1299. Western blot analysis of mouse recombinant TPO.

TPO (N-19) - sc-1298 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TPO (N-19): sc-1298. Western blot analysis of mouse recombinant TPO fusion protein.

Anti-Thrombopoietin antibody - ab40664 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Thrombopoietin antibody - ab93909 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Thrombopoietin antibody (ab93909) at 1 µg/ml + Liver (Human) Tissue Lysate - adult normal tissue (ab29889) at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutionPerformed under reducing conditions.

Anti-Thrombopoietin antibody - ab180728 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Thrombopoietin antibody (ab180728) at 1/500 dilution + 293 cell lysate

Anti-Thrombopoietin antibody - ab84446 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-Thrombopoietin antibody - ab135663 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Thrombopoietin antibody (ab135663) at 1/50 dilutionLane 1 : 293 cell lysate, non-transfectedLane 2 : 293 cell lysate, transiently transfected with the Thrombopoietin geneLysates/proteins at 2 µg per lane.

Anti-Thrombopoietin antibody - ab62796 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Thrombopoietin antibody [1B11] - ab128487 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B11
ELISA using ab128487.

Anti-Thrombopoietin antibody (Biotin) - ab84445 from Abcam

Prices $370.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-Thrombopoietin antibody [EPR14948] - ab196026 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14948
Immunofluorescent analysis of Jurkat cells (4% Paraformaldehyde-fixed, 0.1% tritonX-100 permeabilized) labeling Thrombopoietin with ab196026 at 1/50 dilution followed by Goat anti rabbit IgG (AlexaFluor® 488) (ab150077) secondary at 1/400 dilution and counter-stained with DAPI (blue).Note: Cytoplasm staining on Jurkat cell line was observed.

Anti-Thrombopoietin antibody [MM0566-1Z3] - ab89801 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0566-1Z3

Anti-THPO / TPO / Thrombopoietin Antibody (aa14-29) - LS-C39624 from LifeSpan Bioscience

Prices $405.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal

Anti-THPO / TPO / Thrombopoietin Antibody - LS-C39626 from LifeSpan Bioscience

Prices $405.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal

Anti-THPO / TPO / Thrombopoietin Antibody (aa14-29) - LS-C39625 from LifeSpan Bioscience

Prices $680.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-THPO / TPO / Thrombopoietin Antibody - LS-C39627 from LifeSpan Bioscience

Prices $680.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-THPO / TPO / Thrombopoietin Antibody (aa244-277) - LS-C39628 from LifeSpan Bioscience

Prices $405.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal

Anti-THPO / TPO / Thrombopoietin Antibody (aa244-277) - LS-C39629 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-THPO / TPO / Thrombopoietin Antibody - LS-C39630 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-THPO / TPO / Thrombopoietin Antibody - LS-C39631 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-THPO / TPO / Thrombopoietin Antibody - LS-C39632 from LifeSpan Bioscience

Prices $635.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-THPO / TPO / Thrombopoietin Antibody - LS-C39633 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-THPO / TPO / Thrombopoietin Antibody (aa14-29) - LS-C39634 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
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