THPO

Gene Symbol THPO
Entrez Gene 7066
Alt Symbol MGDF, MKCSF, ML, MPLLG, THCYT1, TPO
Species Human
Gene Type protein-coding
Description thrombopoietin
Other Description MPL ligand|c-mpl ligand|megakaryocyte colony-stimulating factor|megakaryocyte growth and development factor|megakaryocyte stimulating factor|myeloproliferative leukemia virus oncogene ligand|prepro-thrombopoietin
Swissprots P40225 B7ZLR8 A1L3Y0 Q15791 Q15792 Q15790 B9EGA8 Q13020
Accessions AAA74083 AAB33390 AAC37568 BAA06807 EAW78243 EAW78244 EAW78245 P40225 AA479058 AA480029 AB014681 BAA34930 AB014682 BAA34931 AB014683 BAA34932 AB102890 BAD89419 AB102892 BAD89421 AB102894 BAD89423 AK311002 BC130322 AAI30323 BC136338 AAI36339 BC143982 AAI43983 BX108191 D32047 BAA21930 L33410 AAA59857 L36052 AAC37566 U11025 AAA50553 U42977 U59493 AAB03392 U59494 AAB03393 U59495 AAB03394 XM_011513113 XP_011511415 NM_000460 NP_000451 NM_001177597 NP_001171068 NM_001177598 NP_001171069 NM_001289997 NP_001276926 NM_001289998 NP_001276927 NM_001290003 NP_001276932 NM_001290022 NP_001276951 NM_001290026 NP_001276955 NM_001290027 NP_001276956 NM_001290028 NP_001276957 NM_199228 NM_199356
Function Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
Subcellular Location Secreted.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage

TPO CRISPR/Cas9 KO Plasmid (h) - sc-417243 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPO HDR Plasmid (h) - sc-417243-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPO Double Nickase Plasmid (h) - sc-417243-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPO Double Nickase Plasmid (h2) - sc-417243-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPO CRISPR Activation Plasmid (h) - sc-417243-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPO CRISPR Activation Plasmid (h2) - sc-417243-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPO Lentiviral Activation Particles (h) - sc-417243-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPO Lentiviral Activation Particles (h2) - sc-417243-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPO siRNA (h) - sc-39807 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TPO shRNA Plasmid (h) - sc-39807-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TPO shRNA (h) Lentiviral Particles - sc-39807-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU123581 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21322 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21322 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12121 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr12121

THPO siRNA (Human) - CRH4835 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

THPO - MBS8219593 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human THPO (NM_000460.2) - SHH427000 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human THPO(NM_000460.2) - SHL069708 from Creative biogene

Category siRNA
Species Reactivities Human

Human THPO siRNA - orb265337 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

THPO shRNA Plasmid (Human) - CHH4835 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

THPO miRNA 3'UTR clone - MiUTR1H-10386 from Creative biogene

Species Reactivities Human
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