STYK1

Gene Symbol STYK1
Entrez Gene 55359
Alt Symbol NOK, SuRTK106
Species Human
Gene Type protein-coding
Description serine/threonine/tyrosine kinase 1
Other Description novel oncogene with kinase domain|protein PK-unique|tyrosine-protein kinase STYK1
Swissprots Q9NSH1 B2R9T2 Q9BXY2 Q6J9G0 Q52LR3
Accessions EAW96200 Q6J9G0 AF251059 AAK34949 AK313906 BAG36629 AL353940 CAB89250 AM393808 CAL38683 AY563054 AAT01226 BC093822 AAH93822 BC093824 AAH93824 KP729000 AJM21857 XM_005253417 XP_005253474 XM_011520736 XP_011519038 XM_011520737 XP_011519039 XM_011520738 XP_011519040 XM_011520739 XP_011519041 NM_018423 NP_060893
Function Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways (By similarity). {ECO:0000250}.
Subcellular Location Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Widely expressed. Highly expressed in brain, placenta and prostate. Expressed in tumor cells such as hepatoma cells L-02, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K-562, but not in other tumor cells such as epidermoid carcinoma (A-431). Undetectable in most normal lung tissues, widely expressed in lung cancers. {ECO:0000269|PubMed:12841579, ECO:0000269|PubMed:15150103, ECO:0000269|PubMed:17298854}.

Human Styk1 full length protein - ab132571 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab132571 stained with Coomassie Blue.

Human Styk1 protein fragment - ab125536 from Abcam

Category Protein
Source Baculovirus infected sf9 cells
Species Human
SDS-PAGE analysis of ab125536.

Human Styk1 protein fragment - ab163082 from Abcam

Category Protein
Source Wheat germ
Species Human
ab163082 on a 12.5% SDS-PAGE stained with Coomassie Blue.

STYK1 Antibody Blocking Peptide - LS-E9228 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

STYK1 Antibody Blocking Peptide - LS-E17199 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human STYK1 Protein - H00055359-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human STYK1 Protein - H00055359-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

STYK1 Peptide - P2775 from Novus Biologicals

Category Peptide
Species Human

STYK1-Antibody-N-term-Blocking-Peptide - BP7729a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

STYK1 Blocking Peptide - 33R-7060 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

STYK1 / NOK - H00055359-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

STYK1 / NOK - H00055359-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

STYK1 / NOK - H00055359-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

STYK1 / NOK - H00055359-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

STYK1 fusion protein - ag12594 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human STYK1, GST-tagged - STYK1-7023H from Creative Biomart

Category Protein
Source Sf9 Cells
Species Human

Recombinant Human STYK1, GST-tagged - STYK1-3038H from Creative Biomart

Category Protein
Source E.coli
Species Human

STYK1 (NOK) protein-GST fusion - 009-001-T65 from Rockland Immunochemicals Inc

Category Protein
Prices $499.00
Sizes 50 µg
Species Human

STYK1 (NOK) protein-GST fusion - 009-001-T65S from Rockland Immunochemicals Inc

Category Protein
Prices $265.00
Sizes 20 µg
Species Human

STYK1 / NOK - TP310846 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
STYK1 / NOK

STYK1 Recombinant Protein Antigen - NBP2-13398PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

STYK1 Peptide, Human - M34GP15374H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

STYK1(NOK), Recombinant Protein - MBS515289 from MyBioSource

Category Protein
Prices $260.00, $415.00
Sizes 20 µg, 50 µg
Source Sf9 insect cells using baculovirus
Species Human
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