STYK1

Gene Symbol	STYK1
Entrez Gene	55359
Alt Symbol	NOK, SuRTK106
Species	Human
Gene Type	protein-coding
Description	serine/threonine/tyrosine kinase 1
Other Description	novel oncogene with kinase domain|protein PK-unique|tyrosine-protein kinase STYK1
Swissprots	Q9NSH1 B2R9T2 Q9BXY2 Q6J9G0 Q52LR3
Accessions	EAW96200 Q6J9G0 AF251059 AAK34949 AK313906 BAG36629 AL353940 CAB89250 AM393808 CAL38683 AY563054 AAT01226 BC093822 AAH93822 BC093824 AAH93824 KP729000 AJM21857 XM_005253417 XP_005253474 XM_011520736 XP_011519038 XM_011520737 XP_011519039 XM_011520738 XP_011519040 XM_011520739 XP_011519041 NM_018423 NP_060893
Function	Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways (By similarity). {ECO:0000250}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity	Widely expressed. Highly expressed in brain, placenta and prostate. Expressed in tumor cells such as hepatoma cells L-02, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K-562, but not in other tumor cells such as epidermoid carcinoma (A-431). Undetectable in most normal lung tissues, widely expressed in lung cancers. {ECO:0000269|PubMed:12841579, ECO:0000269|PubMed:15150103, ECO:0000269|PubMed:17298854}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NOK CRISPR/Cas9 KO Plasmid (h) - sc-408571 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

NOK HDR Plasmid (h) - sc-408571-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NOK Double Nickase Plasmid (h) - sc-408571-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NOK Double Nickase Plasmid (h2) - sc-408571-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NOK CRISPR Activation Plasmid (h) - sc-408571-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

NOK CRISPR Activation Plasmid (h2) - sc-408571-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

NOK Lentiviral Activation Particles (h) - sc-408571-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NOK Lentiviral Activation Particles (h2) - sc-408571-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NOK siRNA (h) - sc-95937 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

NOK shRNA Plasmid (h) - sc-95937-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

NOK shRNA (h) Lentiviral Particles - sc-95937-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

STYK1 RNAi - H00055359-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

STYK1 RNAi - H00055359-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU003211 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK2214 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK2215 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK2213 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN20798 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20798 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR13090 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr13090

STYK1 siRNA (Human) - CRJ0686 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

STYK1 - MBS8223895 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human STYK1 (NM_018423.2) - SHH420520 from Creative biogene Category siRNA Species Reactivities Human

Human STYK1 siRNA - orb271187 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

STYK1 shRNA Plasmid (Human) - CHJ0686 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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