PXDN

Gene Symbol	PXDN
Entrez Gene	7837
Alt Symbol	COPOA, D2S448, D2S448E, MG50, PRG2, PXN, VPO
Species	Human
Gene Type	protein-coding
Description	peroxidasin
Other Description	melanoma-associated antigen MG50|p53-responsive gene 2 protein|peroxidasin homolog|vascular peroxidase 1
Swissprots	A8QM65 Q92626 D6W4Y0 Q4KMG2
Accessions	EAX01084 EAX01085 Q92626 AF200348 AAF06354 AK098167 BC009496 AAH09496 BC030834 BC041027 BC070119 BC098579 AAH98579 BC140295 AAI40296 BG706125 BX348948 CN359024 CN359026 D86983 BAA13219 DA551404 DA866300 EF090903 ABO25865 XM_005264707 XP_005264764 XM_011510395 XP_011508697 XM_011510396 XP_011508698 XM_011510397 XP_011508699 NM_012293 NP_036425
Function	Displays low peroxidase activity and is likely to participate in H(2)O(2) metabolism and peroxidative reactions in the cardiovascular system. Plays a role in extracellular matrix formation. {ECO:0000269|PubMed:18929642, ECO:0000269|PubMed:19590037}.
Subcellular Location	Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:19590037, ECO:0000269|Ref.8}. Note=Enriched in the peritubular space of fibrotic kidneys.
Tissue Specificity	Expressed at higher levels in heart, lung, ovary, spleen, intestine and placenta, and at lower levels in liver, colon, pancreas, kidney, thymus, skeletal muscle and prostate. Expressed in tumors such as melanoma, breast cancer, ovarian cancer and glioblastoma. A shorter form probably lacking the signal sequence is found in testis and in EB1 cells undergoing p53/TP53-dependent apoptosis. {ECO:0000269|PubMed:10441517, ECO:0000269|PubMed:11103812, ECO:0000269|PubMed:18929642, ECO:0000269|PubMed:19590037}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PXDN protein fragment - ab159891 from Abcam Category Protein Source Wheat germ Species Human

PXN / Paxillin Antibody Blocking Peptide - LS-E8228 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Paxillin Protein - H00005829-P02 from Novus Biologicals Category Protein Prices $315.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Paxillin Protein - H00005829-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human PRG2 Protein - H00005553-Q01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human PXDN Protein - H00007837-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Paxillin Protein - H00005829-P03 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Paxillin Peptide - P2053 from Novus Biologicals Category Peptide Species Human

Paxillin Peptide - P2052 from Novus Biologicals Category Peptide Species Human

Human Peroxidasin Homolog Protein - abx068474 from Abbexa Category Protein Source E.coli Species Human

Human Peroxidasin Homolog Protein - abx068473 from Abbexa Category Protein Source E.coli Species Human

PXDN - H00007837-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PXDN - H00007837-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human Paxillin - 230-00595-10 from RayBiotech Category Protein Prices $110.00 Sizes 10 µg Source Escherichia coli (E.coli) Species Human

Recombinant Human Paxillin - 230-00595-100 from RayBiotech Category Protein Prices $336.00 Sizes 100 µg Source Escherichia coli (E.coli) Species Human

Recombinant Human Paxillin - 230-00595-250 from RayBiotech Category Protein Prices $1,343.00 Sizes 250 µg Source Escherichia coli (E.coli) Species Human

Recombinant Human Paxillin - 230-00595-50 from RayBiotech Category Protein Prices $224.00 Sizes 50 µg Source Escherichia coli (E.coli) Species Human

Peroxidasin Homolog (PXDN), Human - 20-9511 from ARP American Research Products Category Protein Prices $499.00 Sizes 50 µg Source E.coli Species Human

Peroxidasin Homolog (PXDN), Human - 20-9512 from ARP American Research Products Category Protein Prices $499.00 Sizes 50 µg Source E.coli Species Human

PXDN fusion protein - ag19155 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

PXDN fusion protein - ag19044 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Peroxidasin Homolog (PXDN) - RPM070Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Peroxidasin Homolog (PXDN) - RPM070Hu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

IL-1RA - PPT-25675 from Nordic BioSite Category Protein

Recombinant Paxillin (Pax) - RPB844Hu01 from Cloud-clone Category Protein Source E.coli Species Human

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