PXDN

Gene Symbol PXDN
Entrez Gene 7837
Alt Symbol COPOA, D2S448, D2S448E, MG50, PRG2, PXN, VPO
Species Human
Gene Type protein-coding
Description peroxidasin
Other Description melanoma-associated antigen MG50|p53-responsive gene 2 protein|peroxidasin homolog|vascular peroxidase 1
Swissprots A8QM65 Q92626 D6W4Y0 Q4KMG2
Accessions EAX01084 EAX01085 Q92626 AF200348 AAF06354 AK098167 BC009496 AAH09496 BC030834 BC041027 BC070119 BC098579 AAH98579 BC140295 AAI40296 BG706125 BX348948 CN359024 CN359026 D86983 BAA13219 DA551404 DA866300 EF090903 ABO25865 XM_005264707 XP_005264764 XM_011510395 XP_011508697 XM_011510396 XP_011508698 XM_011510397 XP_011508699 NM_012293 NP_036425
Function Displays low peroxidase activity and is likely to participate in H(2)O(2) metabolism and peroxidative reactions in the cardiovascular system. Plays a role in extracellular matrix formation. {ECO:0000269|PubMed:18929642, ECO:0000269|PubMed:19590037}.
Subcellular Location Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:19590037, ECO:0000269|Ref.8}. Note=Enriched in the peritubular space of fibrotic kidneys.
Tissue Specificity Expressed at higher levels in heart, lung, ovary, spleen, intestine and placenta, and at lower levels in liver, colon, pancreas, kidney, thymus, skeletal muscle and prostate. Expressed in tumors such as melanoma, breast cancer, ovarian cancer and glioblastoma. A shorter form probably lacking the signal sequence is found in testis and in EB1 cells undergoing p53/TP53-dependent apoptosis. {ECO:0000269|PubMed:10441517, ECO:0000269|PubMed:11103812, ECO:0000269|PubMed:18929642, ECO:0000269|PubMed:19590037}.

MG50 CRISPR/Cas9 KO Plasmid (h) - sc-404707 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MG50 HDR Plasmid (h) - sc-404707-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MG50 Double Nickase Plasmid (h) - sc-404707-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MG50 Double Nickase Plasmid (h2) - sc-404707-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MG50 CRISPR Activation Plasmid (h) - sc-404707-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MG50 CRISPR Activation Plasmid (h2) - sc-404707-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MG50 Lentiviral Activation Particles (h) - sc-404707-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MG50 Lentiviral Activation Particles (h2) - sc-404707-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PXDN RNAi - H00007837-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Paxillin RNAi - H00005829-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU004721 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17760 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17760 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PXDN siRNA (Human) - CRH5288 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PXDN RNAi - H00007837-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

PXDN siRNA (h) - sc-270608 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PXDN shRNA Plasmid (h) - sc-270608-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PXDN shRNA (h) Lentiviral Particles - sc-270608-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

shRNA set against Human PXDN (NM_012293.1) - SHH387284 from Creative biogene

Category siRNA
Species Reactivities Human

Human PXDN siRNA - orb265790 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PXDN shRNA Plasmid (Human) - CHH5288 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PXDN miRNA 3'UTR clone - MiUTR1H-08511 from Creative biogene

Species Reactivities Human
Search more