BCAS2

Gene Symbol BCAS2
Entrez Gene 10286
Alt Symbol DAM1, SPF27, Snt309
Species Human
Gene Type protein-coding
Description breast carcinoma amplified sequence 2
Other Description DNA amplified in mammary carcinoma 1 protein|breast carcinoma-amplified sequence 2|pre-mRNA-splicing factor SPF27|spliceosome associated protein, amplified in breast cancer|spliceosome-associated protein SPF 27
Swissprots Q6FGS0 O75934
Accessions CAH05197 EAW56602 EAW56603 EAW56604 O75934 AB020623 BAA34863 AB451245 BAG70059 AB451369 BAG70183 AF081788 AAC64059 AK222637 BAD96357 AK313141 BAG35960 BC005285 AAH05285 BC012623 AAH12623 BC022880 AAH22880 BC039238 BF184377 BT019390 AAV38197 CR542037 CAG46834 DQ892529 ABM83455 EU176700 ABW03501 EU832613 ACE87704 EU832684 ACE87016 NM_005872 NP_005863
Function Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR). {ECO:0000269|PubMed:24332808}.
Subcellular Location Nucleus, nucleolus {ECO:0000269|PubMed:12169396, ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:20176811}.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:10403562}.
Top Pathways Spliceosome

BCAS2 (G-8) - sc-365346 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BCAS2 (G-8): sc-365346. Western blot analysis of BCAS2 expression in MCF7 (A), HeLa (B) and K-562 (C) whole cell lysates.

BCAS2 (C-17) - sc-103407 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BCAS2 (C-17): sc-103407. Western blot analysis of BCAS2 expression in non-transfected: sc-117752 (A) and human BCAS2 transfected: sc-172935 (B) 293T whole cell lysates.

BCAS2 (F-5) - sc-376554 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BCAS2 (F-5): sc-376554. Western blot analysis of BCAS2 expression in HEK293 whole cell lysate (A) and SH-SY5Y (B), MCF7 (C), HeLa (D) and K-562 (E) nuclear extracts.

BCAS2 (H-181) - sc-292534 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BCAS2 (H-181): sc-292534. Western blot analysis of BCAS2 expression in HEK293 (A) and HEL 92.1.7 (B) whole cell lysates.

BCAS2 (N-17) - sc-103408 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BCAS2 (N-17): sc-103408. Western blot analysis of BCAS2 expression in non-transfected: sc-117752 (A) and human BCAS2 transfected: sc-172935 (B) 293T whole cell lysates.

Anti-BCAS2 antibody - ab151293 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-BCAS2 antibody (ab151293) at 1/1000 dilution + MCF7 whole cell lysate at 30 µg

Anti-BCAS2 antibody - ab71161 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human small cell lung cancer (left) and mouse squamous cell carcinoma (right) tissues labelling BCAS2 at 1/5000 (0.2µg/ml). Detection: DAB.

Anti-BCAS2 antibody - ab14000 from Abcam

Prices $406.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-BCAS2 antibody - ab84449 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab84449, at 1/250 dilution, staining BCAS2 in formalin-fixed, paraffin-embedded human breast carcinoma tissue by Immunohistochemistry using DAB detection.

Anti-BCAS2 antibody - ab83566 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-BCAS2 antibody (ab83566) at 1 µg/ml + Human fetal liver lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-BCAS2 antibody - ab85708 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-BCAS2 antibody (ab85708) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal brain lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-BCAS2 antibody - ab56694 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-BCAS2 antibody [EPR4375] - ab108330 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4375
Immunofluorescent staining of HeLa cells using ab108330 at a dilution of 1/250.

Anti-BCAS2 antibody [EPR4376] - ab133282 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4376
All lanes : Anti-BCAS2 antibody [EPR4376] (ab133282) at 1/1000 dilutionLane 1 : SH-SY5Y cell lysate Lane 2 : MCF-7 cell lysate Lane 3 : SKBR-3 cell lysate Lane 4 : C6 cell lysate Lane 5 : PC-12 cell lysate SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-BCAS2 Antibody (aa221-235) - LS-C46902 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BCAS2 Antibody (C-Terminus) - LS-C74674 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BCAS2 Antibody (aa21-49, AP) - LS-C233088 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCAS2 Antibody (aa21-49, FITC) - LS-C233090 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCAS2 Antibody (aa21-49, APC) - LS-C233089 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCAS2 Antibody (C-Terminus) - LS-C101861 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
BCAS2 antibody LS-C101861 Western blot of Fetal Liver lysate.

Anti-BCAS2 Antibody (Internal, clone EPR4376) - LS-C137836 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4376
Western blot analysis on (A) SH-SY5Y, (B) MCF-7, and (C) SKBR-3, (D) C6, and (E) PC-12 cell lysates using anti-BCAS2 antibody.

Anti-BCAS2 Antibody (N-Terminus) - LS-C101862 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
BCAS2 antibody LS-C101862 Western blot of Fetal Brain lysate.

Anti-BCAS2 Antibody (aa21-49, Biotin) - LS-C233091 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCAS2 Antibody (aa21-49, PE) - LS-C233096 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCAS2 Antibody (aa21-49, Azide-free, HRP) - LS-C249510 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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