Gene Symbol | BCAS2 |
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Entrez Gene | 10286 |
Alt Symbol | DAM1, SPF27, Snt309 |
Species | Human |
Gene Type | protein-coding |
Description | breast carcinoma amplified sequence 2 |
Other Description | DNA amplified in mammary carcinoma 1 protein|breast carcinoma-amplified sequence 2|pre-mRNA-splicing factor SPF27|spliceosome associated protein, amplified in breast cancer|spliceosome-associated protein SPF 27 |
Swissprots | Q6FGS0 O75934 |
Accessions | CAH05197 EAW56602 EAW56603 EAW56604 O75934 AB020623 BAA34863 AB451245 BAG70059 AB451369 BAG70183 AF081788 AAC64059 AK222637 BAD96357 AK313141 BAG35960 BC005285 AAH05285 BC012623 AAH12623 BC022880 AAH22880 BC039238 BF184377 BT019390 AAV38197 CR542037 CAG46834 DQ892529 ABM83455 EU176700 ABW03501 EU832613 ACE87704 EU832684 ACE87016 NM_005872 NP_005863 |
Function | Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR). {ECO:0000269|PubMed:24332808}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:12169396, ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:20176811}. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:10403562}. |
Top Pathways | Spliceosome |
Human BCAS2 full length protein - ab172154 from Abcam
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Human BCAS2 full length protein - ab124869 from Abcam
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BCAS2 Antibody Blocking Peptide - LS-E3339 from LifeSpan Bioscience
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BCAS2 Antibody Blocking Peptide - LS-E14852 from LifeSpan Bioscience
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BCAS2 Antibody Blocking Peptide - LS-E14853 from LifeSpan Bioscience
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BCAS2 Antibody Blocking Peptide - LS-E30873 from LifeSpan Bioscience
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BCAS2 Partial Recombinant Protein - H00010286-Q01 from Novus Biologicals
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BCAS2 Recombinant Protein - H00010286-P01 from Novus Biologicals
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BCAS2 Peptide - NBP1-77124PEP from Novus Biologicals
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Recombinant Human BCAS2 Protein - NBP1-50992 from Novus Biologicals
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BCAS2-Antibody-N-term-Blocking-Peptide - BP14509a from Abgent, a WuXi AppTec company
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BCAS2 Protein (OPPA00069) - OPPA00069 from Aviva Systems Biology
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Human BCAS2 protein - orb49225 from Biorbyt
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Human BCAS2 protein - orb167954 from Biorbyt
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BCAS2 peptide - orb218329 from Biorbyt
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BCAS2 Blocking Peptide - 33R-5671 from Fitzgerald
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BCAS2 Blocking Peptide - 33R-8559 from Fitzgerald
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BCAS2 protein (His tag) - 80R-1672 from Fitzgerald
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BCAS2 Blocking Peptide - abx063660 from Abbexa
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BCAS2 / DAM1 (1-225, His-tag) - AR09854PU-N from Acris Antibodies
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BCAS2 / DAM1 (1-225, His-tag) - AR09854PU-S from Acris Antibodies
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BCAS2 / DAM1 - H00010286-P01-10 from Acris Antibodies
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BCAS2 / DAM1 - H00010286-P01-25 from Acris Antibodies
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BCAS2 / DAM1 - H00010286-Q01-10 from Acris Antibodies
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BCAS2 / DAM1 - H00010286-Q01-25 from Acris Antibodies
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