COL25A1

Gene Symbol COL25A1
Entrez Gene 84570
Alt Symbol AMY, CFEOM5, CLAC, CLAC-P, CLACP
Species Human
Gene Type protein-coding
Description collagen, type XXV, alpha 1
Other Description alzheimer disease amyloid-associated protein|collagen alpha-1(XXV) chain|collagen-like Alzheimer amyloid plaque component|collagenous Alzheimer amyloid plaque component
Swissprots Q9BXR9 Q9BXS0 A8MPZ6
Accessions AAY40947 EAX06238 EAX06239 EAX06240 Q9BXS0 AF293340 AAK35008 AF293341 AAK35009 AK095098 BC030649 BC036669 AAH36669 XM_011532332 XP_011530634 XM_011532333 XP_011530635 XM_011532334 XP_011530636 XM_011532335 XP_011530637 XM_011532336 XP_011530638 XM_011532337 XP_011530639 XM_011532338 XP_011530640 XM_011532339 XP_011530641 XM_011532340 XP_011530642 XM_011532341 XP_011530643 XM_011532342 XP_011530644 XM_011532343 XP_011530645 XM_011532344 XP_011530646 XM_011532345 XP_011530647 XM_011532346 XP_011530648 XM_011532347 XP_011530649 XM_011532348 XP_011530650 XM_011532349 XP_011530651 XM_011532350 XP_011530652 XM_011532351 XP_011530653 XM_011532352 XP_011530654 XM_011532353 XP_011530655 XM_011532354 XP_011530656 XM_011532355 XP_011530657 XM_011532356 XP_011530658 XM_011532357 XP_011530659 XM_011532358 XP_011530660 XM_011532359 XP_011530661 XR_938784 XR_938785 XR_938786 XR_938787 XR_938788 NM_001256074 NP_001243003 NM_032518 NP_115907 NM_198721 NP_942014 NR_045756
Function Inhibits fibrillization of beta amyloid peptide during the elongation phase. Has also been shown to assemble amyloid fibrils into protease-resistant aggregates. Binds heparin. {ECO:0000269|PubMed:15522881, ECO:0000269|PubMed:15615705, ECO:0000269|PubMed:15853808, ECO:0000269|PubMed:16300410}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Note=After proteolytic cleavage, CLAC is secreted.
Tissue Specificity Expressed predominantly in brain. Deposited preferentially in primitive or neuritic amyloid plaques which are typical of Alzheimer disease. {ECO:0000269|PubMed:11927537}.

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Noelin (OLFM1), Human, ELISA Kit - CSB-EL016320HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t
Sensitivity 5.8 pg/ml
Range 23.5 pg/ml-1500 pg/ml

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Collagen Autoantibody, ELISA Kit - MBS041253 from MyBioSource

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