COL25A1

Gene Symbol	COL25A1
Entrez Gene	84570
Alt Symbol	AMY, CFEOM5, CLAC, CLAC-P, CLACP
Species	Human
Gene Type	protein-coding
Description	collagen, type XXV, alpha 1
Other Description	alzheimer disease amyloid-associated protein|collagen alpha-1(XXV) chain|collagen-like Alzheimer amyloid plaque component|collagenous Alzheimer amyloid plaque component
Swissprots	Q9BXR9 Q9BXS0 A8MPZ6
Accessions	AAY40947 EAX06238 EAX06239 EAX06240 Q9BXS0 AF293340 AAK35008 AF293341 AAK35009 AK095098 BC030649 BC036669 AAH36669 XM_011532332 XP_011530634 XM_011532333 XP_011530635 XM_011532334 XP_011530636 XM_011532335 XP_011530637 XM_011532336 XP_011530638 XM_011532337 XP_011530639 XM_011532338 XP_011530640 XM_011532339 XP_011530641 XM_011532340 XP_011530642 XM_011532341 XP_011530643 XM_011532342 XP_011530644 XM_011532343 XP_011530645 XM_011532344 XP_011530646 XM_011532345 XP_011530647 XM_011532346 XP_011530648 XM_011532347 XP_011530649 XM_011532348 XP_011530650 XM_011532349 XP_011530651 XM_011532350 XP_011530652 XM_011532351 XP_011530653 XM_011532352 XP_011530654 XM_011532353 XP_011530655 XM_011532354 XP_011530656 XM_011532355 XP_011530657 XM_011532356 XP_011530658 XM_011532357 XP_011530659 XM_011532358 XP_011530660 XM_011532359 XP_011530661 XR_938784 XR_938785 XR_938786 XR_938787 XR_938788 NM_001256074 NP_001243003 NM_032518 NP_115907 NM_198721 NP_942014 NR_045756
Function	Inhibits fibrillization of beta amyloid peptide during the elongation phase. Has also been shown to assemble amyloid fibrils into protease-resistant aggregates. Binds heparin. {ECO:0000269|PubMed:15522881, ECO:0000269|PubMed:15615705, ECO:0000269|PubMed:15853808, ECO:0000269|PubMed:16300410}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Note=After proteolytic cleavage, CLAC is secreted.
Tissue Specificity	Expressed predominantly in brain. Deposited preferentially in primitive or neuritic amyloid plaques which are typical of Alzheimer disease. {ECO:0000269|PubMed:11927537}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CLACP full length protein - ab164614 from Abcam Category Protein Source Wheat germ Species Human

Human CLACP protein fragment - ab164615 from Abcam Category Protein Source Wheat germ Species Human

OLFM1 Antibody Blocking Peptide - LS-E7032 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

OLFM1 Antibody Blocking Peptide - LS-E7033 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

OLFM1 Antibody Blocking Peptide - LS-E24059 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

OLFM1 Antibody Blocking Peptide - LS-E24060 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

COL25A1 / Collagen XXV Antibody Blocking Peptide - LS-E18090 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Collagen XXV alpha 1 Protein - H00084570-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human Collagen XXV alpha 1 Protein - H00084570-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Collagen type XXV alpha 1 chain - H00084570-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

Collagen type XXV alpha 1 chain - H00084570-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Collagen type XXV alpha 1 chain - H00084570-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

COL25A1 fusion protein - Ag3634 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, T-HIS Species Human

Recombinant Human COL25A1, His-tagged - COL25A1-11430H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Collagen alpha-1(XXV) chain(COL25A1) - CSB-YP866308HU CSB-EP866308HU CSB-BP866308HU CSB-MP866308HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Collagen XXV alpha 1 Protein - NBP1-91033PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

COL25A1-Antibody-N-term-Blocking-Peptide - BP6964a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

COL25A1 Peptide, Human - M34GP03450H from Creative Peptides Category Peptide Source Synthetic. Species Human

Collagen 25 alpha 1 Blocking Peptide - CBP7493 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse

Collagen alpha-1 (XXV) chain (COL25A1), Recombinant Protein - MBS1284178 from MyBioSource Category Protein Prices $1,390.00, $1,390.00, $1,620.00, $1,620.00, $2,345.00, $2,345.00, $2,790.00, $2,790.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

COL25A1 peptide - orb382398 from Biorbyt Category Peptide Species Human, Mouse

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