IL22RA2

Gene Symbol	IL22RA2
Entrez Gene	116379
Alt Symbol	CRF2-10, CRF2-S1, CRF2X, IL-22BP, IL-22R-alpha-2, IL-22RA2, ZCYTOR16
Species	Human
Gene Type	protein-coding
Description	interleukin 22 receptor, alpha 2
Other Description	cytokine receptor class-II member 10\|cytokine receptor family type 2, soluble 1\|interleukin 22-binding protein\|interleukin-22 receptor subunit alpha-2
Swissprots	Q6UWM1 Q969J5 Q96A41 Q08AH7 Q96QR0
Accessions	AAV31775 CAH61626 CAH61631 CAL60107 CAP40188 CBM42925 EAW47933 EAW47934 EAW47935 Q969J5 AI824338 AJ297262 CAC83097 AJ313161 CAC85634 AJ313162 CAC85635 AY040566 AAK85714 AY040567 AAK85715 AY040568 AAK85716 AY044429 AAK91775 AY358111 AAQ88478 AY358737 AAQ89097 BC125167 AAI25168 BC125168 AAI25169 NM_052962 NP_443194 NM_181309 NP_851826 NM_181310 NP_851827
Function	Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses.
Subcellular Location	Secreted {ECO:0000269\|PubMed:12700595}.
Tissue Specificity	Expressed in placenta, spleen, breast, skin and lung. Also detected in intestinal tract, testis, brain, heart and thymus. No expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus. Isoform 1 is expressed only in placenta. Isoform 2 is expressed in placenta and breast and at lower level in spleen, skin, thymus and stomach. {ECO:0000269\|PubMed:11481447, ECO:0000269\|PubMed:11607789, ECO:0000269\|PubMed:15201862}.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

IL22RA2 - MBS1271789 from MyBioSource

Prices	$175.00
Sizes	10ug plasmid + 200ul glycerol stock
Species	Human
Accession	BC125167

Human IL22RA2 cDNA clone(NM_052962.2) - CDFG007130 from Creative Biomart

Species	Human
Accession	NM_052962.2

Human IL22RA2 cDNA clone(NM_181309.1) - CDFG011614 from Creative Biomart

Species	Human
Accession	NM_181309.1

Human IL22RA2 cDNA clone(NM_181310.1) - CDFG011616 from Creative Biomart

Species	Human
Accession	NM_181310.1

Human IL22RA2 ORF Clone(NM_052962.2) - CDCR314441 from Creative Biomart

Species	Human
Accession	NM_052962.2

Human IL22RA2 ORF Clone(NM_052962.2) - CDCR314442 from Creative Biomart

Species	Human
Accession	NM_052962.2

Human IL22RA2 ORF Clone(NM_181309.1) - CDCR323713 from Creative Biomart

Species	Human
Accession	NM_181309.1

Human IL22RA2 ORF Clone(NM_181309.1) - CDCR323714 from Creative Biomart

Species	Human
Accession	NM_181309.1

Human IL22RA2 ORF Clone(NM_181309.1) - CDCR323715 from Creative Biomart

Species	Human
Accession	NM_181309.1

Human IL22RA2 ORF Clone(NM_181310.1) - CDCR323716 from Creative Biomart

Species	Human
Accession	NM_181310.1

Human IL22RA2 ORF Clone(NM_181310.1) - CDCR323717 from Creative Biomart

Species	Human
Accession	NM_181310.1

Human IL22Ra2 ORF clone(NM_052962.2) - CDCL184853 from Creative Biomart

Species	Human
Accession	NM_052962.2

Human IL-22BP/IL-22RA2 transcript variant 1 Gene ORF cDNA clone in cloning vector - HG10781-M from Sino Biological

Species	Human

Human IL-22BP/IL-22RA2 transcript variant 2 Gene ORF cDNA clone in cloning vector - HG11025-M from Sino Biological

Species	Human

Human IL-22BP/IL-22RA2 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10781-M-F from Sino Biological

Species	Human

The plasmid was transfected into 293H adherent cells with Sinofection reagent (Cat# STF01). After 48 h, Immunofluorescence staining of cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with Mouse anti-Flag Tag monoclonal antibody (CST#8146S) at 37℃ 1 hour. Then cells were stained with Goat Anti-mouse IgG secondary antibody. The fluorescent signal is detected by fluorescence microscope. Each expression experiment has negative control.

Human IL-22BP/IL-22RA2 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11025-NF from Sino Biological

Species	Human

Human IL-22BP/IL-22RA2 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11025-NM from Sino Biological

Species	Human

Human IL-22BP/IL-22RA2 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11025-CF from Sino Biological

Species	Human

Human IL-22BP/IL-22RA2 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10781-NF from Sino Biological

Species	Human

Human IL-22BP/IL-22RA2 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10781-NM from Sino Biological

Species	Human

Human IL-22BP/IL-22RA2 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11025-CM from Sino Biological

Species	Human

Human IL-22BP/IL-22RA2 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10781-CF from Sino Biological

Species	Human

Human IL-22BP/IL-22RA2 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10781-CY from Sino Biological

Species	Human

Human IL-22BP/IL-22RA2 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-His tag - HG10781-NH from Sino Biological

Species	Human

Human IL-22BP/IL-22RA2 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11025-CY from Sino Biological

Species	Human

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