RAB43

Gene Symbol	RAB43
Entrez Gene	339122
Alt Symbol	RAB11B, RAB41
Species	Human
Gene Type	protein-coding
Description	RAB43, member RAS oncogene family
Other Description	ras-related protein Rab-41\|ras-related protein Rab-43
Swissprots	Q86YS6 E9PBQ0 A8K4P9
Accessions	EAW79283 Q86YS6 AK128345 AK291014 BAF83703 AY166852 AAO17291 BC062319 AAH62319 BC073812 BX331971 CA450364 D45418 DA008447 DA103180 DA317502 DA339537 DA757569 DB220260 NM_001204883 NP_001191812 NM_001204884 NP_001191813 NM_001204885 NP_001191814 NM_001204886 NP_001191815 NM_001204887 NP_001191816 NM_001204888 NP_001191817 NM_198490 NP_940892
Function	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. {ECO:0000269\|PubMed:17562788, ECO:0000269\|PubMed:17684057, ECO:0000269\|PubMed:18664496, ECO:0000269\|PubMed:21255211}.
Subcellular Location	Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Golgi apparatus, trans-Golgi network. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis.
Tissue Specificity	Widely expressed in brain, testis, lung, heart, ovary, colon, kidney, uterus and spleen but not in liver. {ECO:0000269\|PubMed:15018353}.

Rab 43 (T-13) - sc-100113 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Rab 43 (T-13): sc-100113. Western blot analysis of Rab 43 expression in mouse testis tissue extract.

Rab 43 (V-17) - sc-100114 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Rab 43 (QK-07) - sc-81923 from Santa Cruz Biotechnology

Prices	$295.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

Rab 43 (QK-07): sc-81923. Western blot analysis of Rab 43 expression in Hep G2 whole cell lysate.

Anti-RAB43 antibody - ab58030 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

RAB43 antibody (ab58030) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human salivary gland.

Anti-RAB43 Antibody (clone 5G4) - LS-C133853 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	5G4

Immunoperoxidase of monoclonal antibody to RAB43 on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml].

RAB43 Antibody (5G4) - H00339122-M01 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	5G4

Western Blot: RAB43 Antibody (5G4) [H00339122-M01] - RAB43 monoclonal antibody (M01), clone 5G4 Analysis of RAB43 expression in HepG2.

RAB43 Antibody - NBP2-13194 from Novus Biologicals

Host	Rabbit
Clonality	Polyclonal

Western Blot: RAB43 Antibody [NBP2-13194] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4

RAB41 Antibody - NBP1-86528 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry: RAB41 Antibody [NBP1-86528] - Staining of human colon shows strong cytoplasmic positivity with a granular pattern in glandular cells.

RAB43 Antibody - H00339122-B01 from Novus Biologicals

Prices	$349.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Western Blot: RAB43 Antibody [H00339122-B01] - analysis of RAB43 expression in transfected 293T cell line by RAB43 MaxPab polyclonal antibody (B01). Lane 1: RAB43 transfected lysate (23.30 KDa). Lane 2: Non-transfected lysate.

RAB43 Antibody - H00339122-D01P from Novus Biologicals

Prices	$399.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western Blot: RAB43 Antibody [H00339122-D01P] - Analysis of RAB43 expression in transfected 293T cell line by RAB43 polyclonal antibody.Lane 1: RAB43 transfected lysate(23.30 KDa).Lane 2: Non-transfected lysate.

RAB43 Antibody (4C11) - H00339122-M09 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	4C11

Sandwich ELISA: RAB43 Antibody (4C11) [H00339122-M09] - Detection limit for recombinant GST tagged RAB43 is approximately 1ng/ml as a capture antibody.

RAB43 Antibody - H00339122-A01 from Novus Biologicals

Prices	$269.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Anti-RAB43 antibody produced in rabbit - SAB1410679 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-RAB43: <B>Cat. No. SAB1410679</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~23.3 kDa using RAB43 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Monoclonal Anti-RAB43 antibody produced in mouse - SAB1405401 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	4C11

<B>Immunoblotting</B><BR/>Monoclonal Anti-RAB43: <B>Cat. No. SAB1405401</B>: Antibody concentration: 1 μg/mL. Specific band of ~36.9 kDa using immunogen protein lysate.

Monoclonal Anti-RAB43 antibody produced in mouse - WH0339122M1 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	5G4

<B>Immunoblotting</B><BR/>Monoclonal Anti-RAB43, <B>Cat. No. WH0339122M1</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~23.3 kDa using HepG2 lysate.

Anti-RAB43 (191-202) antibody produced in rabbit - SAB1105912 from Sigma-Aldrich

Prices	$279.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

RAB43 Antibody - C-terminal region (ARP66654_P050) - ARP66654_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

RAB43-Antibody-monoclonal-M09 - AT3529a from Abgent, a WuXi AppTec company

Prices	$315.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	4C11

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.52 KDa) .

RAB43-Antibody-monoclonal-M01 - AT3528a from Abgent, a WuXi AppTec company

Prices	$315.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	5G4

RAB41 antibody - 70R-19716 from Fitzgerald

Prices	$375.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

RAB43 antibody - 70R-19717 from Fitzgerald

Prices	$375.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

RAB41 Antibody - abx014799 from Abbexa

Host	Rabbit
Clonality	Polyclonal

RAB41 Antibody - abx028854 from Abbexa

Host	Rabbit
Clonality	Polyclonal

RAB41 antibody - AP32330PU-N from Acris Antibodies

Prices	$430.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Immunhistochemistry analysis in human prostate tissue (Formalin-fixed, Paraffin-embedded) using RAB41 antibody Cat.-No. AP32330PU-N.

RAB41 antibody - H00347517-B01P from Acris Antibodies

Prices	$1,530.00
Sizes	500 µg
Host	Mouse
Clonality	Polyclonal

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