VPS4A

Gene Symbol VPS4A
Entrez Gene 27183
Alt Symbol SKD1, SKD1A, SKD2, VPS4, VPS4-1
Species Human
Gene Type protein-coding
Description vacuolar protein sorting 4 homolog A (S. cerevisiae)
Other Description SKD1-homolog|hVPS4|vacuolar protein sorting factor 4A|vacuolar protein sorting-associated protein 4A|vacuolar sorting protein 4
Swissprots Q9UN37 B2RCB7 Q8TF07 Q9Y582 Q9UI03
Accessions AAG01470 EAW83261 EAW83262 EAW83263 EAW83264 Q9UN37 AF112215 AAF17203 AF132747 AAL75948 AF155740 AAD42971 AF159063 AAD49227 AF255952 AAK52408 AK000200 BAA91005 AK025850 AK315026 BAG37514 AL133634 CAB63758 BC013021 BC035121 AAH35121 BC047932 AAH47932 EU831747 ACE86581 NM_013245 NP_037377
Function Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Involved in cytokinesis: retained at the midbody by ZFYVE19/ANCHR and CHMP4C until abscission checkpoint signaling is terminated at late cytokinesis. It is then released following dephosphory
Subcellular Location Prevacuolar compartment membrane; Peripheral membrane protein. Late endosome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Midbody. Note=Membrane-associated in the prevacuolar endosomal compartment. Localizes to the midbody of dividing cells, interaction with ZFYVE19/ANCHR mediates retention at midbody (PubMed:24814515). Localized in two distinct rings on either side of the Fleming body. {ECO:0000269|PubMed:24814515}.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:10637304, ECO:0000269|PubMed:11563910}.
Top Pathways Endocytosis

vacuolar protein sorting 4 homolog A (S. cerevisiae) , ELISA Kit - MBS9322824 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1 ng/ml.
Range 0.25 ng/ml - 8 ng/ml.

Human VPS4A ELISA Kit - E102691 from Biobool

Category ELISA Kit

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9354788 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9366342 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9356389 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9356073 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9360649 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9343716 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9362429 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9352041 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9364026 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9350997 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9347443 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9359250 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9361176 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9351621 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9367651 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9363748 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9374639 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9367624 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9364888 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9369472 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4A (VPS4A), ELISA Kit - MBS9358645 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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