Gene Symbol | MOGAT2 |
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Entrez Gene | 80168 |
Alt Symbol | DGAT2L5, MGAT2 |
Species | Human |
Gene Type | protein-coding |
Description | monoacylglycerol O-acyltransferase 2 |
Other Description | 2-acylglycerol O-acyltransferase 2|acyl CoA:monoacylglycerol acyltransferase 2|acyl-CoA:monoacylglycerol acyltransferase 2|diacylglycerol O-acyltransferase candidate 5|diacylglycerol acyltransferase 2-like protein 5|hDC5|hMGAT2 |
Swissprots | Q86UH6 Q9H630 A8K7I3 Q3SYC2 Q3SYC1 Q6ZQZ2 |
Accessions | CBF67540 CBF90899 CBU92413 CBV04419 EAW74982 EAW74983 Q3SYC2 AK000245 AK026297 BAB15436 AK128620 BAC87534 AK291998 BAF84687 AY157608 AAO23672 BC103876 AAI03877 BC103877 AAI03878 BC103878 AAI03879 XM_011545267 XP_011543569 XR_950059 NM_025098 NP_079374 |
Function | Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity. {ECO:0000269|PubMed:12621063}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:12621063}; Multi-pass membrane protein {ECO:0000269|PubMed:12621063}. |
Tissue Specificity | Highly expressed in liver, small intestine, colon, stomach and kidney. {ECO:0000269|PubMed:12621063, ECO:0000269|PubMed:12824082}. |
Top Pathways | Fat digestion and absorption, Glycerolipid metabolism |
MGAT2 (C-20) - sc-32392 from Santa Cruz Biotechnology
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MGAT2 (H-80) - sc-66963 from Santa Cruz Biotechnology
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MGAT2 (L-20) - sc-32391 from Santa Cruz Biotechnology
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MGAT2 (H-25) - sc-130817 from Santa Cruz Biotechnology
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Anti-MOGAT2 antibody - ab84656 from Abcam
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Anti-MOGAT2 antibody - ab106247 from Abcam
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Anti-MOGAT2 antibody - Carboxyterminal end - ab63156 from Abcam
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Anti-MOGAT2 Antibody - LS-C309043 from LifeSpan Bioscience
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Anti-MOGAT2 Antibody (aa180-229) - LS-C102348 from LifeSpan Bioscience
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Anti-MOGAT2 Antibody - LS-C332717 from LifeSpan Bioscience
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Anti-MOGAT2 Antibody (aa278-312) - LS-C98664 from LifeSpan Bioscience
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Anti-MOGAT2 Antibody (aa165-175) IHC-plus⢠- LS-B9222 from LifeSpan Bioscience
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MOGAT2 Antibody - NBP1-85230 from Novus Biologicals
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MGAT2 Antibody - NBP2-14235 from Novus Biologicals
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MOGAT2 Antibody - NBP1-52078 from Novus Biologicals
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MOGAT2 Antibody - NBP2-19377 from Novus Biologicals
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MOGAT2 Antibody - H00080168-B01P from Novus Biologicals
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Anti-MOGAT2 antibody produced in rabbit - HPA028834 from Sigma-Aldrich
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Anti-MOGAT2 antibody produced in goat - SAB2501644 from Sigma-Aldrich
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Anti-MOGAT2 antibody produced in mouse - SAB1408012 from Sigma-Aldrich
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MOGAT2 antibody - middle region (ARP49925_P050) - ARP49925_P050 from Aviva Systems Biology
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MOGAT2-Antibody-internal-region - AF3311a from Abgent, a WuXi AppTec company
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MGAT2 antibody [N1C1] - GTX114926 from GeneTex
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MOGAT2 antibody - GTX117145 from GeneTex
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MOGAT2 antibody - orb20649 from Biorbyt
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