Gene Symbol | MOGAT2 |
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Entrez Gene | 80168 |
Alt Symbol | DGAT2L5, MGAT2 |
Species | Human |
Gene Type | protein-coding |
Description | monoacylglycerol O-acyltransferase 2 |
Other Description | 2-acylglycerol O-acyltransferase 2|acyl CoA:monoacylglycerol acyltransferase 2|acyl-CoA:monoacylglycerol acyltransferase 2|diacylglycerol O-acyltransferase candidate 5|diacylglycerol acyltransferase 2-like protein 5|hDC5|hMGAT2 |
Swissprots | Q86UH6 Q9H630 A8K7I3 Q3SYC2 Q3SYC1 Q6ZQZ2 |
Accessions | CBF67540 CBF90899 CBU92413 CBV04419 EAW74982 EAW74983 Q3SYC2 AK000245 AK026297 BAB15436 AK128620 BAC87534 AK291998 BAF84687 AY157608 AAO23672 BC103876 AAI03877 BC103877 AAI03878 BC103878 AAI03879 XM_011545267 XP_011543569 XR_950059 NM_025098 NP_079374 |
Function | Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity. {ECO:0000269|PubMed:12621063}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:12621063}; Multi-pass membrane protein {ECO:0000269|PubMed:12621063}. |
Tissue Specificity | Highly expressed in liver, small intestine, colon, stomach and kidney. {ECO:0000269|PubMed:12621063, ECO:0000269|PubMed:12824082}. |
Top Pathways | Fat digestion and absorption, Glycerolipid metabolism |
Human MGAT2 full length protein - ab158887 from Abcam
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Human MOGAT2 full length protein - ab164209 from Abcam
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Human MOGAT2 protein fragment - ab164210 from Abcam
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MGAT2 Antibody Blocking Peptide - LS-E16422 from LifeSpan Bioscience
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MGAT2 Antibody Blocking Peptide - LS-E16421 from LifeSpan Bioscience
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MOGAT2 Antibody Blocking Peptide - LS-E853 from LifeSpan Bioscience
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MOGAT2 Antibody Blocking Peptide - LS-E27460 from LifeSpan Bioscience
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MOGAT2 Antibody Blocking Peptide - LS-E18029 from LifeSpan Bioscience
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MGAT2 Recombinant Protein - H00004247-P01 from Novus Biologicals
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Recombinant Human MOGAT2 Protein - H00080168-Q01 from Novus Biologicals
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Recombinant Human MOGAT2 Protein - H00080168-P01 from Novus Biologicals
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MOGT2-Antibody-N-term-Blocking-peptide - BP11666a from Abgent, a WuXi AppTec company
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MGAT2 Blocking Peptide - 33R-10048 from Fitzgerald
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MGAT2 Blocking Peptide - 33R-7174 from Fitzgerald
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MOGAT2 Blocking Peptide - 33R-5142 from Fitzgerald
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MOGAT2 Peptide - AC21-2284-P from Abcore
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MOGAT2 - H00080168-P01-10 from Acris Antibodies
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MOGAT2 - H00080168-P01-25 from Acris Antibodies
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MOGAT2 - H00080168-Q01-10 from Acris Antibodies
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MOGAT2 - H00080168-Q01-25 from Acris Antibodies
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MOGAT2 Peptide - 42-646P from ProSci
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MOGAT2 fusion protein - ag15806 from Proteintech Group
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MOGAT2 fusion protein - Ag16923 from Proteintech Group
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Recombinant Human MGAT2 - BP001311-C824 from Syd Labs
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Recombinant Monoacylglycerol-O-acyltransferase 2 (MOGAT2) - RPH629Hu01 from Uscn Life Science Inc.
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