| Gene Symbol |
RPS6KA6
|
| Entrez Gene |
27330
|
| Alt Symbol |
PP90RSK4, RSK4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ribosomal protein S6 kinase, 90kDa, polypeptide 6
|
| Other Description |
90 kDa ribosomal protein S6 kinase 6|RSK-4|S6K-alpha 6|S6K-alpha-6|p90-RSK 6|p90RSK6|ribosomal S6 kinase 4|ribosomal protein S6 kinase alpha-6
|
| Swissprots |
Q6FHX2 B2R854 Q9H4S6 B7ZL90 Q8WX28 Q9UK32
|
| Accessions |
CAJ32899 EAW98575 Q9UK32 AF184965 AAF13190 AK023104 AK026301 AK310346 AK313240 BAG36051 BC143647 BC143648 AAI43649 BC146380 AAI46381 BC148802 AAI48803 BQ448025 CR536566 CAG38803 XM_011530917 XP_011529219 XM_011530918 XP_011529220 XM_011530919 XP_011529221 XM_011530920 XP_011529222 NM_014496 NP_055311
|
| Function |
Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis. {ECO:0000269|PubMed:15042092, ECO:0000269|PubMed:15632195}.
|
| Subcellular Location |
Cytoplasm, cytosol {ECO:0000269|PubMed:15632195}. Nucleus {ECO:0000269|PubMed:15632195}. Note=Predominantly cytosolic.
|
| Top Pathways |
Long-term potentiation, Progesterone-mediated oocyte maturation, MAPK signaling pathway, Neurotrophin signaling pathway, Oocyte meiosis
|