Gene Symbol | RPS6KA6 |
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Entrez Gene | 27330 |
Alt Symbol | PP90RSK4, RSK4 |
Species | Human |
Gene Type | protein-coding |
Description | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
Other Description | 90 kDa ribosomal protein S6 kinase 6|RSK-4|S6K-alpha 6|S6K-alpha-6|p90-RSK 6|p90RSK6|ribosomal S6 kinase 4|ribosomal protein S6 kinase alpha-6 |
Swissprots | Q6FHX2 B2R854 Q9H4S6 B7ZL90 Q8WX28 Q9UK32 |
Accessions | CAJ32899 EAW98575 Q9UK32 AF184965 AAF13190 AK023104 AK026301 AK310346 AK313240 BAG36051 BC143647 BC143648 AAI43649 BC146380 AAI46381 BC148802 AAI48803 BQ448025 CR536566 CAG38803 XM_011530917 XP_011529219 XM_011530918 XP_011529220 XM_011530919 XP_011529221 XM_011530920 XP_011529222 NM_014496 NP_055311 |
Function | Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis. {ECO:0000269|PubMed:15042092, ECO:0000269|PubMed:15632195}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:15632195}. Nucleus {ECO:0000269|PubMed:15632195}. Note=Predominantly cytosolic. |
Top Pathways | Long-term potentiation, Progesterone-mediated oocyte maturation, MAPK signaling pathway, Neurotrophin signaling pathway, Oocyte meiosis |
Active human RSK4 full length protein - ab85296 from Abcam
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Human RSK4 peptide - ab45389 from Abcam
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Human RSK4 protein fragment - ab153295 from Abcam
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RSK4 Partial Recombinant Protein - H00027330-Q01 from Novus Biologicals
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RSK4 Peptide - P2932 from Novus Biologicals
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RSK4-Antibody-N-term-Blocking-Peptide - BP7944a from Abgent, a WuXi AppTec company
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Human RSK4 GST tag protein - orb83699 from Biorbyt
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RPS6KA6 / RSK4 - H00027330-Q01-10 from Acris Antibodies
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RPS6KA6 / RSK4 - H00027330-Q01-25 from Acris Antibodies
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RPS6KA6 / RSK4 - P5638 from Acris Antibodies
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RPS6KA6 fusion protein - ag16299 from Proteintech Group
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RPS6KA6 fusion protein - Ag17382 from Proteintech Group
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Recombinant Human RPS6KA6, GST-tagged, Active - RPS6KA6-427H from Creative Biomart
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Recombinant Human RPS6KA6, GST tagged - RPS6KA6-3329H from Creative Biomart
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Recombinant Human RPS6KA6 - RPS6KA6-30418TH from Creative Biomart
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Recombinant Human RPS6KA6, His-tagged - RPS6KA6-2436H from Creative Biomart
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Rsk4 Protein, active, 10 µg - 14-702 from EMD Millipore
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Rsk4 Protein, active, 250 µg - 14-702M from EMD Millipore
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Rsk-4 (Q688) Peptide - BS2507P from Bioworld Technology
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Recombinant Human Ribosomal protein S6 kinase alpha-6(RPS6KA6) - CSB-YP891943HU CSB-EP891943HU CSB-BP891943HU CSB-MP891943HU from Cusabio
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RSK4 Blocking Peptide - CBP4220 from Cohesion Biosciences
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RSK4 Blocking Peptide - abx161431 from Abbexa
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RPS6KA6 / RSK4 - TP311545 from Acris Antibodies
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Human RSK4 / RPS6KA6 Protein (GST Tag) - 10147-H09B-20 from Sino Biological
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Recombinant Human RSK4 / RPS6KA6 Protein (GST tag) - PKSH030423 from Elabscience
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