Gene Symbol | RPS6KA6 |
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Entrez Gene | 27330 |
Alt Symbol | PP90RSK4, RSK4 |
Species | Human |
Gene Type | protein-coding |
Description | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
Other Description | 90 kDa ribosomal protein S6 kinase 6|RSK-4|S6K-alpha 6|S6K-alpha-6|p90-RSK 6|p90RSK6|ribosomal S6 kinase 4|ribosomal protein S6 kinase alpha-6 |
Swissprots | Q6FHX2 B2R854 Q9H4S6 B7ZL90 Q8WX28 Q9UK32 |
Accessions | CAJ32899 EAW98575 Q9UK32 AF184965 AAF13190 AK023104 AK026301 AK310346 AK313240 BAG36051 BC143647 BC143648 AAI43649 BC146380 AAI46381 BC148802 AAI48803 BQ448025 CR536566 CAG38803 XM_011530917 XP_011529219 XM_011530918 XP_011529220 XM_011530919 XP_011529221 XM_011530920 XP_011529222 NM_014496 NP_055311 |
Function | Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis. {ECO:0000269|PubMed:15042092, ECO:0000269|PubMed:15632195}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:15632195}. Nucleus {ECO:0000269|PubMed:15632195}. Note=Predominantly cytosolic. |
Top Pathways | Long-term potentiation, Progesterone-mediated oocyte maturation, MAPK signaling pathway, Neurotrophin signaling pathway, Oocyte meiosis |
Rsk-4 (C-20) - sc-17178 from Santa Cruz Biotechnology
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Rsk-4 (N-20) - sc-17176 from Santa Cruz Biotechnology
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Rsk-4 (JS-31) - sc-100424 from Santa Cruz Biotechnology
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Anti-RSK4 (phospho S235) antibody [EP1524Y] - ab81290 from Abcam
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Anti-RSK4 antibody - ab57231 from Abcam
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Anti-RSK4 antibody - ab199134 from Abcam
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Anti-RSK4 antibody - ab69929 from Abcam
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Anti-RSK4 antibody - ab42100 from Abcam
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Anti-RSK4 antibody [EP1982Y] - ab76117 from Abcam
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Anti-RPS6KA6 / RSK4 Antibody (Gln688) - LS-C177029 from LifeSpan Bioscience
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Anti-RPS6KA6 / RSK4 Antibody (N-Terminus, clone EP1982Y) - LS-C50052 from LifeSpan Bioscience
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Anti-RPS6KA6 / RSK4 Antibody (N-Terminus) - LS-C17733 from LifeSpan Bioscience
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Anti-RPS6KA6 / RSK4 Antibody - LS-C38970 from LifeSpan Bioscience
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Anti-RPS6KA6 / RSK4 Antibody - LS-C93400 from LifeSpan Bioscience
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Anti-RPS6KA6 / RSK4 Antibody (clone 8H5) - LS-C133729 from LifeSpan Bioscience
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Anti-RPS6KA6 / RSK4 Antibody (clone 6F2) - LS-C133728 from LifeSpan Bioscience
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Anti-RPS6KA6 / RSK4 Antibody (clone 8E8) - LS-C133730 from LifeSpan Bioscience
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Anti-RPS6KA6 / RSK4 Antibody (aa661-710) - LS-C119317 from LifeSpan Bioscience
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Anti-RPS6KA6 / RSK4 Antibody (phospho-Ser235, clone EP1524Y) - LS-C50095 from LifeSpan Bioscience
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RSK Antibody [Unconjugated] - AF889 from Novus Biologicals
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RSK Antibody (792921) - Pan Specific - MAB2056 from Novus Biologicals
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RSK4 Antibody (374521) - MAB3916 from Novus Biologicals
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RSK Antibody - Pan Specific - AF2056 from Novus Biologicals
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RSK4 Antibody - NBP1-87107 from Novus Biologicals
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RSK4 Antibody (6F2) - H00027330-M02 from Novus Biologicals
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