VWF

Gene Symbol	VWF
Entrez Gene	7450
Alt Symbol	F8VWF, VWD
Species	Human
Gene Type	protein-coding
Description	von Willebrand factor
Other Description	coagulation factor VIII VWF
Swissprots	Q8TCE8 P04275 Q99806
Accessions	AAA61294 AAA61295 AAB59458 AEY75227 CAA29985 CBX54458 CCQ25771 CDI44165 EAW88814 EAW88815 EAW88816 EAW88817 EAW88818 P04275 AF086470 AK292122 BAF84811 AK297600 BAG59985 AK298097 BAG60382 AK301216 BAG62791 BC022258 AAH22258 BG951111 BQ898017 DB293903 GU014837 ACX32324 K03028 AAA61293 M10321 AAB59512 M17588 AAA65940 U81237 AAB39987 X02672 CAA26503 X04146 CAA27765 X04385 CAA27972 NM_000552 NP_000543
Function	Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
Subcellular Location	Secreted {ECO:0000269|PubMed:10961880}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:10961880}. Note=Localized to storage granules.
Tissue Specificity	Plasma.
Top Pathways	Focal adhesion, Complement and coagulation cascades, ECM-receptor interaction, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

VWF-Over-expression-Lysate - LY10379a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

VWF 293T Cell Transient Overexpression Lysate(Denatured) - H00007450-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

VWF 293T Cell Transient Overexpression Lysate(Denatured) - H00007450-T02 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

VWF overexpression lysate - LY424643 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

Von Willebrand Factor Overexpression Lysate (Denatured) - H00007450-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Human vWF CHO Cell Lysate (WB positive control) - 10973-H08CL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human Von Willebrand Factor (VWF) Deficient Plasma (EDTA) - D203004 from AssayPro Category Blood Product Prices $40.00 Sizes 1 ml Species Human Tissue Plasma

Human Von Willebrand Factor (VWF) Deficient Plasma (EDTA) - D203005 from AssayPro Category Blood Product Prices $200.00 Sizes 10 ml Species Human Tissue Plasma

Human Von Willebrand Factor (VWF) Deficient Plasma (EDTA) - D203006 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Plasma

Human Von Willebrand Factor (VWF) Deficient Plasma (Heparin) - D203007 from AssayPro Category Blood Product Prices $40.00 Sizes 1 ml Species Human Tissue Plasma

Human Von Willebrand Factor (VWF) Deficient Plasma (Heparin) - D203008 from AssayPro Category Blood Product Prices $200.00 Sizes 10 ml Species Human Tissue Plasma

Human Von Willebrand Factor (VWF) Deficient Plasma (Heparin) - D203009 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Plasma

Human Von Willebrand Factor (VWF) Deficient Plasma (Sodium Citrate) - D203001 from AssayPro Category Blood Product Prices $40.00 Sizes 1 ml Species Human Tissue Plasma

Human Von Willebrand Factor (VWF) Deficient Plasma (Sodium Citrate) - D203002 from AssayPro Category Blood Product Prices $200.00 Sizes 10 ml Species Human Tissue Plasma

Human Von Willebrand Factor (VWF) Deficient Plasma (Sodium Citrate) - D203003 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Plasma

Human Von Willebrand Factor (VWF) Deficient Serum - D203010 from AssayPro Category Blood Product Prices $40.00 Sizes 1 ml Species Human Tissue Serum

Human Von Willebrand Factor (VWF) Deficient Serum - D203011 from AssayPro Category Blood Product Prices $200.00 Sizes 10 ml Species Human Tissue Serum

Human Von Willebrand Factor (VWF) Deficient Serum - D203012 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Serum

Panoply™ Human VWF Knockdown Stable Cell Line - CSC-DC017371 from Creative biogene Category Cell Line Species Human

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