VWF

Gene Symbol VWF
Entrez Gene 7450
Alt Symbol F8VWF, VWD
Species Human
Gene Type protein-coding
Description von Willebrand factor
Other Description coagulation factor VIII VWF
Swissprots Q8TCE8 P04275 Q99806
Accessions AAA61294 AAA61295 AAB59458 AEY75227 CAA29985 CBX54458 CCQ25771 CDI44165 EAW88814 EAW88815 EAW88816 EAW88817 EAW88818 P04275 AF086470 AK292122 BAF84811 AK297600 BAG59985 AK298097 BAG60382 AK301216 BAG62791 BC022258 AAH22258 BG951111 BQ898017 DB293903 GU014837 ACX32324 K03028 AAA61293 M10321 AAB59512 M17588 AAA65940 U81237 AAB39987 X02672 CAA26503 X04146 CAA27765 X04385 CAA27972 NM_000552 NP_000543
Function Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
Subcellular Location Secreted {ECO:0000269|PubMed:10961880}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:10961880}. Note=Localized to storage granules.
Tissue Specificity Plasma.
Top Pathways Focal adhesion, Complement and coagulation cascades, ECM-receptor interaction, PI3K-Akt signaling pathway

VWF CRISPR/Cas9 KO Plasmid (h) - sc-400217 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

VWF HDR Plasmid (h) - sc-400217-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VWF Double Nickase Plasmid (h) - sc-400217-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VWF Double Nickase Plasmid (h2) - sc-400217-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VWF CRISPR Activation Plasmid (h) - sc-400217-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

VWF CRISPR Activation Plasmid (h2) - sc-400217-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

VWF Lentiviral Activation Particles (h) - sc-400217-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VWF Lentiviral Activation Particles (h2) - sc-400217-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VWF siRNA (h) - sc-36828 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

VWF shRNA Plasmid (h) - sc-36828-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

VWF shRNA (h) Lentiviral Particles - sc-36828-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Von Willebrand Factor RNAi - H00007450-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN1745 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1745 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

VWF siRNA (Human) - CRH5097 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

VWF - MBS8240637 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human VWF (NM_000552.3) - SHH445512 from Creative biogene

Category siRNA
Species Reactivities Human

Human VWF siRNA - orb265599 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

VWF shRNA Plasmid (Human) - CHH5097 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

VWF miRNA 3'UTR clone - MiUTR1H-11180 from Creative biogene

Species Reactivities Human
Search more