VWF

Gene Symbol VWF
Entrez Gene 7450
Alt Symbol F8VWF, VWD
Species Human
Gene Type protein-coding
Description von Willebrand factor
Other Description coagulation factor VIII VWF
Swissprots Q8TCE8 P04275 Q99806
Accessions AAA61294 AAA61295 AAB59458 AEY75227 CAA29985 CBX54458 CCQ25771 CDI44165 EAW88814 EAW88815 EAW88816 EAW88817 EAW88818 P04275 AF086470 AK292122 BAF84811 AK297600 BAG59985 AK298097 BAG60382 AK301216 BAG62791 BC022258 AAH22258 BG951111 BQ898017 DB293903 GU014837 ACX32324 K03028 AAA61293 M10321 AAB59512 M17588 AAA65940 U81237 AAB39987 X02672 CAA26503 X04146 CAA27765 X04385 CAA27972 NM_000552 NP_000543
Function Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
Subcellular Location Secreted {ECO:0000269|PubMed:10961880}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:10961880}. Note=Localized to storage granules.
Tissue Specificity Plasma.
Top Pathways Focal adhesion, Complement and coagulation cascades, ECM-receptor interaction, PI3K-Akt signaling pathway

VWF (C-12) - sc-365712 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VWF (C-12): sc-365712. Western blot analysis of VWF expression in human platelet extract.

VWF (C-20) - sc-8068 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VWF (C-20): sc-8068. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

VWF (F8/44/20) - sc-53465 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

VWF (G-11) - sc-271409 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VWF (G-11): sc-271409. Immunoperoxidase staining of formalin fixed, paraffin-embedded human bone marrow tissue showing cytoplasmic and membrane staining of subset of hematopoietic cells.

VWF (F8/86) - sc-53466 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VWF (F8/86): sc-53466. Western blot analysis of VWF expression in human platelet extract (A) and HUV-EC-C (B) whole cell lysates.

VWF (H-300) - sc-14014 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
VWF (H-300): sc-14014. Immunofluorescence staining of normal mouse heart frozen section showing blood vessel staining.

VWF (3E2D10) - sc-21784 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VWF (3E2D10): sc-21784. Western blot analysis of purified human VWF.

VWF (1.B.690) - sc-73268 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
VWF (1.B.690): sc-73268. Western blot analysis of VWF expression in human platelet extract (A) and HUV-EC-C whole cell lysate (B).

VWF (4F9) - sc-59957 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
VWF (4F9): sc-59957. Western blot analysis of VWF expression in human platelet extract (A) and HUV-EC-C whole cell lysate (B).

VWF (GMA-022) - sc-65973 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
VWF (GMA-022): sc-65973. Western blot analysis of VWF expression in human platelet extract (A) and HUV-EC-C whole cell lysate (B).

VWF (VW28-1) - sc-59810 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-Von Willebrand Factor antibody - ab9378 from Abcam

Prices $392.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human tonsil tissue, staining Von Willebrand Factor with ab9378.

Anti-Von Willebrand Factor antibody - ab11713 from Abcam

Prices $392.00
Sizes 500 µl
Host Sheep
Clonality Polyclonal
ab11713 at a 1/1000 dilution staining Von Willebrand Factor in mouse blood vessels by Immunohistochemistry (frozen sections) incubated for 16 hours at 4°C. PFA fixed. Permeabilized with 0.1% Triton. Blocked using 20% serum for 1 hour at 19°C. Secondary used at 1/200 polyclonal Donkey anti-sheep conjugated to Alexa Fluor 647 (pink). Counterstain (blue) DAPI.See Abreview

Anti-Von Willebrand Factor antibody - ab8820 from Abcam

Prices $369.00
Sizes 1 ml
Host Sheep
Clonality Polyclonal

Anti-Von Willebrand Factor antibody - ab61292 from Abcam

Prices $370.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-Von Willebrand Factor antibody - ab115771 from Abcam

Prices $376.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab115771, at 5 ug/ml, staining Von Willebrand Factor in Formalin-fixed, Paraffin embedded Human Brain Cortex (vessel) by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Von Willebrand Factor antibody - ab47151 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Von Willebrand Factor antibody (ab47151) at 1/1000 dilutionLane 1 : Human serum. Reduced buffer at 1 µlLane 2 : Human serum. Reduced buffer at 0.5 µlLane 3 : Human serum. Reduced buffer at 0.25 µl

Anti-Von Willebrand Factor antibody - ab93708 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab93708, at 1/100 dilution, staining Von Willebrand Factor in formalin-fixed, paraffin-embedded Human colon tissue by Immunohistochemistry.

Anti-Von Willebrand Factor antibody - ab19367 from Abcam

Prices $368.00
Sizes 500 µl
Host Goat
Clonality Polyclonal

Anti-Von Willebrand Factor antibody [2Q2134] - ab68545 from Abcam

Prices $378.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2Q2134

Anti-Von Willebrand Factor antibody [2Q2134] - BSA and Azide free - ab190777 from Abcam

Prices $378.00
Sizes 125 µl
Host Mouse
Clonality Monoclonal
Clone 2Q2134

Anti-Von Willebrand Factor antibody [36B11] - ab49706 from Abcam

Prices $372.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 36B11

Anti-Von Willebrand Factor antibody [3E2D10] - ab194405 from Abcam

Prices $379.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone 3E2D10
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue labeling Von Willebrand Factor with ab194405 at 1.0 µg/mL.

Anti-Von Willebrand Factor antibody [3E2D10 + VWF635] - ab201336 from Abcam

Prices $359.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone 3E2D10 + VWF635
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human tonsil tissue labeling Von Willebrand Factor with ab201336 at 1 µg/ml.

Anti-Von Willebrand Factor antibody [4F9] - ab20435 from Abcam

Prices $379.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4F9
ab20435, staining Von Willebrand Factor (green) in hMSC-TERT, hADMSC, hADSSC and hNFSSC cells by Immunocytochemistry/ Immunofluorescence. Cells were fixed in paraformaldehyde and permeabilized with 0.1% Triton X-100 for 10 min. After washing with PBS, cells were blocked with 3% BSA for 30 min and incubated with primary antibody at 10 µl/ml, at 4°C overnight. A FITC-conjugated goat anti-mouse polyclonal IgG (1/4000) was used as the secondary antibody.
Search more